Department of Tropical Medicine and Infectious Diseases, University of Rostock, Ernst-Heydemann-Strasse 6, Rostock, Germany.
Int J Infect Dis. 2010 Sep;14 Suppl 3:e338-40. doi: 10.1016/j.ijid.2010.03.005. Epub 2010 Jun 26.
A 40-year-old Asian circus elephant developed mouth and trunk ulcers. Three weeks later, her 19-year-old animal warden noticed a vesicle on his forearm, evolving into a scab. Identical cowpox strains were isolated from lesions of the elephant and the warden. Cowpox virus could no longer be isolated after the scab disappeared, but PCR still revealed orthopox DNA. Healing was complete seven weeks later, leaving a 1 cm scar.
一位 40 岁的亚洲马戏团大象出现口腔和象鼻溃疡。三周后,其 19 岁的管理员注意到前臂上出现水疱,随后发展为结痂。从大象和管理员的病变中分离出了相同的牛痘菌株。结痂脱落时,已无法再分离出牛痘病毒,但 PCR 仍显示正痘病毒 DNA。七周后痊愈,留下 1 厘米的疤痕。