Department of Pediatrics, Children's Hospital of Michigan, Wayne State University, Detroit Medical Center, Detroit, Michigan 48201, USA.
Epilepsy Behav. 2010 Jul;18(3):254-61. doi: 10.1016/j.yebeh.2010.02.015. Epub 2010 May 23.
We determined how visuomotor tasks modulated gamma-oscillations on electrocorticography in epileptic patients who underwent epilepsy surgery. Each visual-cue consisted of either a sentence or hand gesture instructing the subject to press or not to press the button. Regardless of the recorded hemisphere, viewing sentence and gesture cues elicited gamma-augmentation sequentially in the lateral-polar occipital and inferior occipital-temporal areas; subsequently, button-press movement elicited gamma-augmentation in the Rolandic area. The magnitudes of gamma-augmentation in the Rolandic and inferior occipital-temporal areas were larger when the hand contralateral to the recorded hemisphere was used for motor responses. A double dissociation was found in the left inferior occipital-temporal cortex in one subject; the lateral portion had greater gamma-augmentation elicited by a sentence-cue, whereas the medial portion had greater gamma-augmentation elicited by a gesture-cue. The present study has increased our understanding of the physiology of the human visuomotor system.
我们确定了视觉运动任务如何调节接受癫痫手术的患者脑电图中的伽马振荡。每个视觉提示由句子或手势组成，指示患者按下或不按下按钮。无论记录的半球如何，观看句子和手势提示都会依次在外侧极地和下颞枕区引起伽马增强；随后，按钮按下运动在 Rolandic 区引起伽马增强。当使用与记录半球相对侧的手进行运动反应时，Rolandic 和下颞枕区的伽马增强幅度更大。在一个被试者的左侧下颞枕皮质中发现了双重分离；外侧部分由句子提示引起的伽马增强更大，而内侧部分由手势提示引起的伽马增强更大。本研究增加了我们对人类视觉运动系统生理学的理解。
