Department of Surgery, Leiden University Medical Centre, P.O. Box 9600, 2300 RC, Leiden, The Netherlands.
World J Surg. 2010 Oct;34(10):2278-85. doi: 10.1007/s00268-010-0694-y.
Acute appendicitis continues to be a challenging diagnosis. Preoperative radiological imaging using ultrasound (US) or computed tomography (CT) has gained popularity as it may offer a more accurate diagnosis than classic clinical evaluation. The optimal implementation of these diagnostic modalities has yet to be established. The aim of the present study was to investigate a diagnostic pathway that uses routine US, limited CT, and clinical re-evaluation for patients with acute appendicitis.
A prospective analysis was performed of all patients presenting with acute abdominal pain at the emergency department from June 2005 until July 2006 using a structured diagnosis and management flowchart. Daily practice was mimicked, while ensuring a valid assessment of clinical and radiological diagnostic accuracies and the effect they had on patient management.
A total of 802 patients were included in this analysis. Additional radiological imaging was performed in 96.3% of patients with suspected appendicitis (n = 164). Use of CT was kept to a minimum (17.9%), with a US:CT ratio of approximately 6:1. Positive and negative predictive values for the clinical diagnosis of appendicitis were 63 and 98%, respectively; for US 94 and 97%, respectively; and for CT 100 and 100%, respectively. The negative appendicitis rate was 3.3%, the perforation rate was 23.5%, and the missed perforated appendicitis rate was 3.4%. No (diagnostic) laparoscopies were performed.
A diagnostic pathway using routine US, limited CT, and clinical re-evaluation for patients with acute abdominal pain can provide excellent results for the diagnosis and treatment of appendicitis.
急性阑尾炎的诊断仍然具有挑战性。术前影像学检查(如超声[US]或计算机断层扫描[CT])已越来越受欢迎,因为它可能比经典的临床评估提供更准确的诊断。这些诊断方法的最佳实施方式尚未确定。本研究旨在探讨一种使用常规 US、有限 CT 和临床重新评估的诊断途径,用于治疗急性阑尾炎患者。
对 2005 年 6 月至 2006 年 7 月在急诊科就诊的所有急性腹痛患者进行前瞻性分析,使用结构化的诊断和管理流程图。模仿日常实践,同时确保对临床和放射学诊断准确性及其对患者管理的影响进行有效评估。
共有 802 例患者纳入本分析。怀疑阑尾炎的患者中有 96.3%(n=164)进行了额外的影像学检查。对 CT 的使用保持在最低限度(17.9%),US 与 CT 的比例约为 6:1。临床诊断阑尾炎的阳性和阴性预测值分别为 63%和 98%;US 分别为 94%和 97%;CT 分别为 100%和 100%。阴性阑尾炎率为 3.3%,穿孔率为 23.5%,漏诊穿孔阑尾炎率为 3.4%。未进行(诊断性)腹腔镜检查。
对于急性腹痛患者,使用常规 US、有限 CT 和临床重新评估的诊断途径可以为阑尾炎的诊断和治疗提供出色的结果。