Department of Otolaryngology/Head and Neck Surgery, Hadassah Hebrew-University Medical Center, Jerusalem, Israel.
Laryngoscope. 2010 Jul;120(7):1428-9. doi: 10.1002/lary.20969.
Acute upper airway obstruction is a potentially life-threatening event. Hemophilia-A is a coagulopathy with high risk for spontaneous bleeding. Here we describe for the first time a spontaneous epiglottic internal hemorrhage leading to upper airway narrowing in a hemophilia-A patient. The patient was admitted to the intensive care unit for airway observation and treatment with factor VIII supplementation. In the first 48 hours there was rapid respiratory improvement. The epiglottic swelling resolved on the 5th day. In this patient no oral intubation or surgical management was needed.
急性上呼吸道梗阻是一种潜在的危及生命的事件。血友病 A 是一种具有自发性出血高风险的凝血障碍。在这里,我们首次描述了一名血友病 A 患者自发性会厌内出血导致上呼吸道狭窄。患者因气道观察和补充因子 VIII 而入住重症监护病房进行治疗。在最初的 48 小时内,呼吸情况迅速改善。第 5 天会厌肿胀消退。在该患者中,无需进行口腔插管或手术治疗。