Gyanesh Prakhar, Dhiraaj Sanjay
Department of Anaesthesiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.
J Anaesthesiol Clin Pharmacol. 2013 Jan;29(1):117-20. doi: 10.4103/0970-9185.105819.
Intracranial hemorrhage in patients with hemophilia is associated with high mortality and sequelae. We report the case of 50-year-old man with Hemophilia A, who presented with spontaneous acute subdural hematoma and underwent craniotomy for clot evacuation. The patient received Factor VIII infusions perioperatively along with other measures to decrease blood loss. The patient presented with signs of high intracranial tension and received 3% saline intraoperatively and postoperatively to prevent brain edema. Recommendations for perioperative preparation and management of hemophilia, especially in the setting of emergency major surgery are reviewed.
血友病患者的颅内出血与高死亡率和后遗症相关。我们报告了一例50岁的甲型血友病男性患者,该患者出现自发性急性硬膜下血肿并接受了开颅血肿清除术。患者在围手术期接受了凝血因子VIII输注以及其他减少失血的措施。患者出现颅内压增高的体征,术中及术后接受了3%盐水治疗以预防脑水肿。本文回顾了血友病围手术期准备和管理的建议,尤其是在急诊大手术的情况下。