INSERM U, Paris Sud Innovation Group in Adolescent Mental Health, Maison de Solenn, Paris, France.
Addict Behav. 2010 Oct;35(10):890-5. doi: 10.1016/j.addbeh.2010.06.001. Epub 2010 Jun 9.
Licit substance use could be an early stage leading on to cannabis use. The aim of the study was to test a hypothetical sequential process leading from socializing to cannabis use so as to evaluate the mediator role of tobacco and alcohol. Data was derived from a French nationwide survey carried out in 2005 involving 29,393 teenagers aged 17. The analysis used structural equation modelling. The sequence tested was: socializing with friends-tobacco/alcohol use-cannabis use-cannabis use disorders (CUD). Tobacco and alcohol consumptions appeared to be similarly influenced by the time spent with friends. However, tobacco mediation explained 57% of the sequence leading to cannabis use and 61% of the sequence leading to CUD, while the role of alcohol was weaker, at around 13%. Our results underline the effect of peer influence, in the course of night-out socializing, on substance use among adolescents, and the importance of tobacco mediation in the process leading to cannabis use and misuse. This suggests that prevention in places frequented by adolescents should primarily target tobacco consumption, which explains the largest part of cannabis use variance. However, processes linking substance uses seem to be more complex, with the existence of reverse pathways from cannabis to licit drugs. Thus, the gateway effects of tobacco and alcohol require further exploration in relation to simultaneous polysubstance use.
合法物质的使用可能是导致大麻使用的早期阶段。本研究旨在检验从社交到大麻使用的假设顺序过程,以评估烟草和酒精的中介作用。数据来自于 2005 年在法国全国范围内进行的一项涉及 29393 名 17 岁青少年的调查。该分析采用结构方程模型。测试的序列为:与朋友社交-吸烟/饮酒-大麻使用-大麻使用障碍(CUD)。烟草和酒精的消费似乎受到与朋友共度时间的相似影响。然而,烟草的中介作用解释了导致大麻使用的序列的 57%和导致 CUD 的序列的 61%,而酒精的作用较弱,约为 13%。我们的研究结果强调了同伴影响在青少年夜生活社交过程中对物质使用的影响,以及烟草中介作用在导致大麻使用和滥用过程中的重要性。这表明,在青少年经常光顾的场所进行预防应主要针对烟草消费,因为烟草消费解释了大麻使用变化的最大部分。然而,物质使用之间的联系过程似乎更加复杂,存在从大麻到合法药物的反向途径。因此,烟草和酒精的门户效应需要进一步探讨与同时使用多种物质的关系。