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巴西大学生中非法药物的使用转换。

Use transition between illegal drugs among Brazilian university students.

机构信息

Interdisciplinary Group of Studies on Alcohol and Drugs (GREA), Institute of Psychiatry, Medical School, University of São Paulo, Rua Dr. Ovídio Pires de Campos, 785 (GREA), São Paulo, SP, 05403-903, Brazil,

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2014 Mar;49(3):385-94. doi: 10.1007/s00127-013-0748-1. Epub 2013 Aug 6.

Abstract

PURPOSE

The aim of the present study was to test whether the first use of an illicit drug increases the chance of first use of other illicit drugs.

METHOD

The transitions from the first use of a drug to the first use of another drug were analyzed. Comparisons were made between first drug users and non-users. Survival analysis methods were used to compare the cumulative probability of second drug use after adjusting for socio-demographic covariates and the intermediate use of alcohol and/or tobacco. A total of 12,721 Brazilian university students participated in this study.

RESULTS

Inhalants and marijuana were used prior to the use of several other drugs, whereas the opposite pattern was not found. Ecstasy was used before other drugs in several instances. Other well-examined drugs, such as amphetamines, cocaine and hallucinogens, were used both before and after other illicit drugs without any marked predominance for either of the two roles.

CONCLUSIONS

This study supports the role of the use of marijuana and inhalants almost exclusively before the use of other illicit drugs, whereas the use of ecstasy has an opposite role. These roles could be linked to the prevalence of lifetime use and whether individuals were at an earlier or later age during experimentation.

摘要

目的

本研究旨在检验首次使用非法药物是否会增加首次使用其他非法药物的可能性。

方法

分析了从首次使用一种药物到首次使用另一种药物的转变。比较了首次使用药物者和非使用者。使用生存分析方法,比较了在调整社会人口学协变量以及中间使用酒精和/或烟草后,第二次使用药物的累积概率。共有 12721 名巴西大学生参与了这项研究。

结果

在使用几种其他药物之前,曾使用过吸入剂和大麻,而不是相反的情况。迷幻剂在某些情况下也在其他药物之前使用。其他经过充分研究的药物,如安非他命、可卡因和致幻剂,在使用其他非法药物之前和之后都有使用,但没有明显的主次之分。

结论

本研究支持大麻和吸入剂的使用几乎完全先于其他非法药物的使用,而迷幻剂的使用则起到相反的作用。这些作用可能与终生使用的流行率以及个体在实验中处于较早或较晚的年龄有关。

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