Department of Anesthesia and Pain Medicine, Ajou University Hospital, San 5 Won-Cheon Dong Pal-Dal Gu, Suwon, Korea 442-721.
Anesth Analg. 2010 Aug;111(2):550-3. doi: 10.1213/ANE.0b013e3181e4204c. Epub 2010 Jun 28.
Ninety-eight patients received 160 mandibular nerve (V3) blocks with alcohol for the treatment of trigeminal neuralgia in this prospective study. According to the Kaplan-Meier analysis, the probabilities of remaining pain free for 1, 2, 3, and 7 years after the procedures were 90.4%, 69%, 53.5%, and 33%, respectively. There was no significant difference in the probability of pain-free duration and complications between patients with repeat versus single V3 block with alcohol. We conclude that single and repeat V3 alcohol block for trigeminal neuralgia can provide long-lasting pain relief.
在这项前瞻性研究中，98 例患者接受了 160 次下颌神经（V3）阻滞酒精注射治疗三叉神经痛。根据 Kaplan-Meier 分析，治疗后 1、2、3 和 7 年时无疼痛的概率分别为 90.4%、69%、53.5%和 33%。重复与单次 V3 阻滞酒精注射治疗的患者在无疼痛持续时间和并发症发生率方面无显著差异。我们得出结论，单次和重复 V3 酒精阻滞治疗三叉神经痛可提供长期的疼痛缓解。
