Department of Physics, King's College London, Strand, London WC2R 2LS, UK.
Photochem Photobiol Sci. 2010 Aug;9(8):1159-66. doi: 10.1039/c0pp00106f. Epub 2010 Jun 29.
Aqueous dispersions of fluorescent semiconducting polymer nanospheres (SPNs) have been synthesised by two methods; miniemulsion and micellar encapsulation. The colloidal and optical stability of SPNs synthesised by these two methods has been compared in order to assess the potential of these fluorescent nanoparticles for use in biological applications. The SPNs were dispersed in water, phosphate buffer solution (PBS) and bovine serum albumin (BSA). The optical stability was studied by absorption and emission spectroscopy, and the colloidal stability was studied by dynamic light scattering (DLS) over a one month period. The results indicate that the micelle-encapsulated SPNs exhibit favourable optical and colloidal stability, and seem promising for use in biological sciences.
荧光半导体聚合物纳米球（SPN）的水分散体已经通过两种方法合成；细乳液法和胶束包封法。为了评估这些荧光纳米粒子在生物应用中的潜力，比较了这两种方法合成的 SPN 的胶体和光学稳定性。将 SPN 分散在水中、磷酸盐缓冲溶液（PBS）和牛血清白蛋白（BSA）中。通过吸收和发射光谱研究了光学稳定性，通过动态光散射（DLS）在一个月的时间内研究了胶体稳定性。结果表明，胶束包封的 SPN 表现出良好的光学和胶体稳定性，有望用于生物科学。
