利用聚电解质生成功能化且稳定的半导体聚合物点。
Generation of functionalized and robust semiconducting polymer dots with polyelectrolytes.
机构信息
Department of Chemistry, University of Washington, Seattle, WA, USA.
出版信息
Chem Commun (Camb). 2012 Mar 28;48(26):3161-3. doi: 10.1039/c2cc17703j. Epub 2012 Feb 20.
Abstract
We describe a facile method to functionalize semiconducting polymer dots (Pdots) with polyelectrolytes. The polyelectrolyte coating dramatically improves the colloidal stability of the Pdots in solutions which are either of high ionic strength or contain bivalent metal ions: this feature allows Pdots to be used under physiologically relevant environments without losing their functionality. We conjugated the polyelectrolyte-coated Pdots with streptavidin to demonstrate their application in specific cell labeling.
摘要
我们描述了一种将聚合物点（Pdots）功能化的简便方法。聚电解质涂层极大地提高了 Pdots 在高离子强度溶液或含有二价金属离子的溶液中的胶体稳定性：这一特性使 Pdots 能够在生理相关环境下使用而不会失去其功能。我们将聚电解质涂层的 Pdots 与链霉亲和素缀合，以证明它们在特定细胞标记中的应用。
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