职业暴露与阻塞性肺疾病:理发师中的病例对照研究。
Occupational exposures and obstructive lung disease: a case-control study in hairdressers.
机构信息
Department of Physiology, Mashhad University of Medical Sciences, Mashhad, Iran, 177948564.
出版信息
Respir Care. 2010 Jul;55(7):895-900.
BACKGROUND
Hairdressers are exposed to various irritating chemicals during work.
OBJECTIVE
This study was designed as a case-control study to evaluate the risk of developing obstructive lung disease in relation to occupational exposures in hairdressers.
METHODS
We interviewed a cohort of 50 female hairdressers and 50 matched controls recruited from a random sample of the general population, using a validated questionnaire for occupational respiratory disease, to compare the prevalence of work-initiated and work-related respiratory symptoms in both groups. We also performed pulmonary function tests (PFTs) in all participants.
RESULTS
Almost half of the hairdressers reported work-initiated respiratory symptoms. Cough (33%) and breathlessness (29%) were the most common self-reported symptoms after chemical exposures. All respiratory symptoms (cough, breathless, wheezing, and phlegm) were significantly higher in the hairdressers than in the control group (P < .001). The hairdressers reported that bleaching powder and hair spray were the most irritant chemicals that provoke their respiratory symptoms. The impaired PFT values (forced vital capacity, FEV(1), maximum mid-expiratory flow, peak expiratory flow) in the hairdressers, compared to the matched controls, were in line with the questionnaire data.
CONCLUSIONS
Hairdressing work is associated with a high frequency of work-initiated respiratory symptoms and, to a lesser extent, with allergic symptoms, particularly after exposure to bleaching powder and hair spray. PFT values were significantly lower among the hairdressers, which might be a predictor for developing obstructive lung disease.
背景
美发师在工作中会接触到各种刺激性化学物质。
目的
本研究设计为病例对照研究,旨在评估美发师职业暴露与阻塞性肺疾病风险的关系。
方法
我们使用经过验证的职业性呼吸道疾病问卷,对 50 名女性美发师和 50 名随机抽取的一般人群对照进行了访谈,以比较两组工作引起和与工作相关的呼吸道症状的患病率。我们还对所有参与者进行了肺功能测试(PFT)。
结果
近一半的美发师报告有工作引起的呼吸道症状。咳嗽(33%)和呼吸困难(29%)是接触化学物质后最常见的自我报告症状。所有呼吸道症状(咳嗽、呼吸困难、喘息和咳痰)在美发师中均显著高于对照组(P <.001)。美发师报告说,漂白粉和发胶是最刺激他们呼吸道症状的化学物质。与匹配的对照组相比,美发师的 PFT 值(用力肺活量、FEV1、最大中期呼气流量、呼气峰流量)受损,与问卷数据一致。
结论
美发工作与工作引起的呼吸道症状的高频率相关,在一定程度上与过敏症状相关,尤其是在接触漂白粉和发胶后。美发师的 PFT 值明显较低,这可能是发展为阻塞性肺疾病的预测因素。