Kobayashi N, Miyachi S, Okamoto T, Hattori K, Kojima T, Hattori K, Nakai K, Qian S, Takeda H, Yoshida J
Nagoya University, Graduate School of Medicine; Japan.
Interv Neuroradiol. 2004 Mar 30;10 Suppl 1(Suppl 1):155-60. doi: 10.1177/15910199040100S127. Epub 2008 Jun 9.
Using a supercomputer, the authors studied the effect of vessel wall pulsation on flow dynamics with a three-dimensional model simulating both a rigid and pulsatile style. The design of the aneurysm models was set with a 5 mm dome diameter and a 1 or 3 mm orifice size to simulate a carotid-ophthalmic aneurysm. Flow dynamics were analyzed according to flow pattern, wall pressure and wall shear stress. The flow pattern in the aneurysm sac showed the great difference between rigid and pulsatile models particularly in the small-neck aneurysm model. The arterial wall tended to be exposed to a higher pressure peak in the pulsatile model than in the rigid one, especially at its bifurcation and curved regions. Sites of shear stress peak were found on the aneurysmal dome as well as at the distal end of the orifice in both rigid and pulsatile models. The effects of vessel-wall pulsation should be considered whenever evaluating conditions in and around an aneurysm.
作者使用超级计算机，通过一个模拟刚性和脉动型的三维模型研究了血管壁脉动对血流动力学的影响。动脉瘤模型的设计设定为穹顶直径5毫米，孔口尺寸1或3毫米，以模拟颈眼动脉瘤。根据血流模式、壁压力和壁剪切应力分析血流动力学。动脉瘤腔内的血流模式在刚性和脉动模型之间显示出很大差异，特别是在小颈动脉瘤模型中。与刚性模型相比，脉动模型中的动脉壁倾向于承受更高的压力峰值，尤其是在其分叉和弯曲区域。在刚性和脉动模型中，剪切应力峰值部位均出现在动脉瘤穹顶以及孔口远端。在评估动脉瘤内部及其周围情况时，应考虑血管壁脉动的影响。
