氯氮平撤药导致的紧张症。
Clozapine-withdrawal catatonia.
机构信息
Dept. of Psychiatry and Biobehavioral Sciences, UCLA, UCLA-Psychiatry Residency Program Education Office (116A3), 16111 Plummer St., Bldg. 10, North Hills, CA 91343, USA.
出版信息
Psychosomatics. 2010 Jul-Aug;51(4):355-355.e2. doi: 10.1176/appi.psy.51.4.355.
BACKGROUND
Case reports in which abrupt clozapine discontinuation led to a return of psychosis, autonomic instability, or catatonia have been previously presented in the literature.
OBJECTIVE
The authors report on symptom presentation and resolution in a case of abrupt withdrawal of clozapine medication.
METHOD
The authors describe the condition and history of the patient, a 49-year-old woman with schizophrenia, the medical support she received, and the re-initiation of her clozapine medication.
RESULTS
Symptoms of catatonia and autonomic instability resolved by Day 4 of treatment.
CONCLUSION
Patients and their caregivers need to be educated about the effects of abrupt cessation of clozapine administration.
背景
文献中曾报道过氯氮平突然停药导致精神病、自主神经不稳定或紧张症复发的病例报告。
目的
作者报告了一例氯氮平药物突然停药后出现的症状表现和缓解情况。
方法
作者描述了一位 49 岁女性精神分裂症患者的病情和病史、她所接受的医疗支持以及氯氮平药物的重新使用。
结果
紧张症和自主神经不稳定的症状在治疗第 4 天得到缓解。
结论
需要对患者及其护理人员进行关于氯氮平突然停药的影响的教育。
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