Klarman Eating Disorders Center, McLean Hospital, Belmont, MA, USA.
Psychiatry Res. 2010 Aug 15;178(3):511-7. doi: 10.1016/j.psychres.2010.05.021. Epub 2010 Jul 1.
The clinical utility of the DSM-IV eating disorder (ED) diagnostic criteria among practicing clinicians has not been formally evaluated, despite the considerable diagnostic challenges these disorders present. This study evaluated inter-rater reliability between research and clinical diagnoses, identified discrepantly rated diagnostic criteria, and evaluated ED subtype use in a naturalistic treatment setting. Seventy-six adolescent and young adult female patients consecutively admitted to a residential ED program were evaluated independently by clinicians (unstructured clinical interview) and research assessors (Structured Clinical Interview for DSM-IV). Clinicians and research assessors conferred concordant ED diagnoses in 80.3% of cases (kappa=0.70), thus highlighting the clinical utility of the extant DSM-IV diagnostic scheme in this specialty ED treatment setting. All but two discordant cases included a diagnosis of ED not otherwise specified (EDNOS). Clinicians applied ED subtypes in just 20.4% of eligible cases, and were significantly more likely to apply subtypes to major depressive disorder. Although clinical and research interviews yielded substantial reliability, EDNOS had the lowest reliability among the ED diagnoses. Moreover, infrequent subtype application on this specialty unit raises questions about the clinical utility of DSM-IV anorexia nervosa and bulimia nervosa subtypes, even in the context of clinically useful overarching categories.
尽管这些疾病存在相当大的诊断挑战,但 DSM-IV 饮食障碍 (ED) 诊断标准在实践临床医生中的临床实用性尚未得到正式评估。本研究评估了研究和临床诊断之间的评分者间可靠性,确定了评分不一致的诊断标准,并在自然治疗环境中评估了 ED 亚型的使用。76 名连续入住住院 ED 项目的青少年和年轻成年女性患者由临床医生(非结构化临床访谈)和研究评估员(DSM-IV 结构化临床访谈)分别进行评估。临床医生和研究评估员在 80.3%的病例中达成了一致的 ED 诊断(kappa=0.70),这突出了现有 DSM-IV 诊断方案在这种专业 ED 治疗环境中的临床实用性。除了两个不一致的病例外,所有病例都包含了未特定的 ED 诊断(EDNOS)。在符合条件的病例中,临床医生仅在 20.4%的病例中应用了 ED 亚型,并且更有可能将亚型应用于重度抑郁症。尽管临床和研究访谈具有很高的可靠性,但 EDNOS 在 ED 诊断中可靠性最低。此外,在这个专业单位中,亚型的应用频率较低,这引发了关于 DSM-IV 神经性厌食症和神经性贪食症亚型的临床实用性的问题,即使在临床上有用的总体类别中也是如此。