Laboratory of Clinical Microbiology, School of Medicine, Democritus University of Thrace, Alexandroupolis 68100, Greece.
J Clin Microbiol. 2010 Sep;48(9):3414-5. doi: 10.1128/JCM.00843-10. Epub 2010 Jun 30.
Detection of the bla(VIM-12) gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.
首次在阴沟肠杆菌临床分离株中检测到最初描述的 Inh12 整合子内的 bla(VIM-12)基因。该整合子 Inh12 位于一个约 85kb 的可转移质粒上,该质粒还赋予对氨曲南的耐药性,可能是由于 AmpC 产生。