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肠杆菌科出现 VIM-12。

Emergence of VIM-12 in Enterobacter cloacae.

机构信息

Laboratory of Clinical Microbiology, School of Medicine, Democritus University of Thrace, Alexandroupolis 68100, Greece.

出版信息

J Clin Microbiol. 2010 Sep;48(9):3414-5. doi: 10.1128/JCM.00843-10. Epub 2010 Jun 30.

DOI:10.1128/JCM.00843-10
PMID:20592145
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2937735/
Abstract

Detection of the bla(VIM-12) gene within the originally described Inh12 integron in a clinical isolate of Enterobacter cloacae is reported for the first time worldwide. Integron Inh12 was carried on a conjugative plasmid of approximately 85 kb which also conferred resistance to aztreonam, likely due to AmpC production.

摘要

首次在阴沟肠杆菌临床分离株中检测到最初描述的 Inh12 整合子内的 bla(VIM-12)基因。该整合子 Inh12 位于一个约 85kb 的可转移质粒上，该质粒还赋予对氨曲南的耐药性，可能是由于 AmpC 产生。

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本文引用的文献

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J Clin Microbiol. 2009 Nov;47(11):3514-9. doi: 10.1128/JCM.01193-09. Epub 2009 Sep 9.
2
Use of boronic acid disk tests to detect extended- spectrum beta-lactamases in clinical isolates of KPC carbapenemase-possessing enterobacteriaceae.使用硼酸盘试验检测产 KPC 碳青霉烯酶肠杆菌科临床分离株中的超广谱β-内酰胺酶。
J Clin Microbiol. 2009 Nov;47(11):3420-6. doi: 10.1128/JCM.01314-09. Epub 2009 Sep 2.
3
Clonal spread of KPC-2 carbapenemase-producing Klebsiella pneumoniae strains in Greece.产KPC-2碳青霉烯酶肺炎克雷伯菌菌株在希腊的克隆传播。
J Antimicrob Chemother. 2009 Aug;64(2):348-52. doi: 10.1093/jac/dkp207. Epub 2009 Jun 13.
4
AmpC beta-lactamases.AmpC β-内酰胺酶
Clin Microbiol Rev. 2009 Jan;22(1):161-82, Table of Contents. doi: 10.1128/CMR.00036-08.
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Emergence of Serratia liquefaciens and Klebsiella oxytoca with metallo-beta-lactamase-encoding IncW plasmids: further spread of the blaVIM-1-carrying integron In-e541.携带金属β-内酰胺酶编码IncW质粒的液化沙雷氏菌和产酸克雷伯菌的出现：携带blaVIM-1的整合子In-e541的进一步传播。
Int J Antimicrob Agents. 2008 Dec;32(6):540-1. doi: 10.1016/j.ijantimicag.2008.06.022. Epub 2008 Sep 10.
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Antimicrob Agents Chemother. 2005 Dec;49(12):5153-6. doi: 10.1128/AAC.49.12.5153-5156.2005.