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肾及输尿管上段结石冲击波碎石术的适应证、成功预测及改善治疗效果的方法

Indications, prediction of success and methods to improve outcome of shock wave lithotripsy of renal and upper ureteral calculi.

作者信息

Skolarikos Andreas, Mitsogiannis Heraklis, Deliveliotis Charalambos

机构信息

2nd Department of Urology, Athens Medical School, Sismanoglio Hospital, Greece.

出版信息

Arch Ital Urol Androl. 2010 Mar;82(1):56-63.

Abstract

OBJECTIVES

To clarify the current indications, factors influencing outcome and methods to predict and improve the results of shock wave lithotripsy for the treatment of renal and upper ureteral calculi.

MATERIAL AND METHODS

English literature on the Medline and MeSH databases was reviewed. Key words used for search included shock wave lithotripsy, calculi, stones, renal, kidney, ureter, efficacy, prediction, improvement and guidelines.

RESULTS

Shock wave lithotripsy still has certain indications for renal and upper ureteral stones. Major impact on outcome has the stone size, with a diameter of less than 20 mm being the cutoff point. Shock wave monotherapy should not be used for larger stones and should be combined with other treatment modalities such as percutaneous nephrolithotomy or ureteroscopy. Other factors influencing outcome include stone number, composition and location, existence of congenital abnormalities, obesity and bleeding diathesis. Nomograms, artificial neural networks and computed tomography are useful adjuncts in predicting the outcome. Potential methods of improvement are the decrease of shock wave rate, the progressive increase in lithotripter output, the use of two simultaneous or sequential pulses and the use of expulsive and chemolytic treatment.

CONCLUSION

Shock wave lithotripsy continues to be a significant part in the urologists armamentarium for the treatment of renal and upper ureteral stones.

摘要

目的

阐明目前冲击波碎石术治疗肾及上段输尿管结石的适应证、影响治疗效果的因素以及预测和改善治疗结果的方法。

材料与方法

检索Medline和医学主题词表(MeSH)数据库中的英文文献。检索关键词包括冲击波碎石术、结石、肾结石、输尿管结石、疗效、预测、改善及指南。

结果

冲击波碎石术对肾及上段输尿管结石仍有一定的适应证。结石大小对治疗效果影响较大,直径小于20mm为临界点。对于较大结石不应单纯采用冲击波碎石术,而应与其他治疗方式如经皮肾镜取石术或输尿管镜检查术联合应用。其他影响治疗效果的因素包括结石数量、成分及位置、是否存在先天性异常、肥胖及出血倾向。列线图、人工神经网络及计算机断层扫描在预测治疗结果方面是有用的辅助手段。可能的改善方法包括降低冲击波频率、逐步增加碎石机输出能量、采用同时或序贯双脉冲以及应用排石和溶石治疗。

结论

冲击波碎石术仍然是泌尿外科医生治疗肾及上段输尿管结石的重要手段。

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