Naqiyah I, Zulkarnaen A N, Rohaizak M, Das S
Hippokratia. 2010 Apr;14(2):141-2.
Thyroid carcinosarcoma (TC) is a very rare, aggressive thyroid malignancy with a clinical course similar to anaplastic carcinoma. A thorough search of the literature reveals limited information regarding its behavior and treatment modalities. TC has a high mortality rate despite the multi-modal approach. A 54-year-old Chinese gentleman with a long history of a nodule in the right lobe of the thyroid presented with recent history of hemoptysis and shortness of breath. Cytology was suggestive of follicular neoplasm. However, histopathological examination of the total thyroidectomy specimen confirmed TC. This case reports discusses the clinical course and management of TC, which can cause a diagnostic dilemma.
甲状腺癌肉瘤(TC)是一种非常罕见的侵袭性甲状腺恶性肿瘤,其临床病程与未分化癌相似。对文献进行全面检索后发现,关于其行为和治疗方式的信息有限。尽管采用了多模式治疗方法,TC的死亡率仍然很高。一名54岁的中国男性,甲状腺右叶有结节病史,近期出现咯血和气短症状。细胞学检查提示为滤泡性肿瘤。然而,全甲状腺切除标本的组织病理学检查证实为TC。本病例报告讨论了TC的临床病程和管理,TC可导致诊断困境。