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犬甲状腺癌肉瘤伪装为食管旁脓肿。

Thyroid carcinosarcoma masquerading as a paraesophageal abscess in a Cane Corso dog.

机构信息

Ulsan S Animal Medical Center, Ulsan 44726, Republic of Korea (Park); S Animal Cancer Center, Yangsan 50614, Republic of Korea (Park); Department of Veterinary Internal Medicine, Konkuk University Veterinary Medical Teaching Hospital, Seoul 05029, Republic of Korea (Nam); Department of Veterinary Diagnostic Imaging (Choi), Department of Veterinary Surgery (Kim, Lee, Jeong), College of Veterinary Medicine, Chungnam National University, Daejeon 34134, Republic of Korea.

出版信息

Can Vet J. 2023 Mar;64(3):257-261.

Abstract

A 12-year-old castrated male Cane Corso dog was presented with cervical swelling, lethargy, anorexia, and cough. An extensive neck mass with necrotic cysts was observed, severely adherent to surrounding tissues. Based on diagnostic imaging including ultrasound, computed tomography, and fine-needle aspiration cytology, paraesophageal abscess was tentatively diagnosed. However, after the mass was surgically removed, a diagnosis of thyroid carcinosarcoma composed of neoplastic cell populations with epithelial and mesenchymal origins was made histopathology and immunohistochemistry. The dog died of a recurrent mass with pulmonary metastasis 105 d after surgery. This report describes a rare type of canine thyroid cancer, thyroid carcinosarcoma, preoperatively masquerading as an abscess and postoperatively confirmed by histopathology. Key clinical message: Thyroid carcinosarcoma, despite its rarity in dogs, should be included in the differential diagnoses of cervical mass especially with an aggressive progression.

摘要

一只 12 岁去势雄性坎高犬出现颈部肿胀、嗜睡、食欲不振和咳嗽。观察到广泛的颈部肿块,伴有坏死性囊肿,与周围组织严重粘连。根据包括超声、计算机断层扫描和细针抽吸细胞学检查在内的诊断影像学检查,初步诊断为食管旁脓肿。然而,在切除肿块后,通过组织病理学和免疫组织化学检查,诊断为由上皮和间充质起源的肿瘤细胞群组成的甲状腺癌肉瘤。术后 105 天,狗因复发性肺转移导致的肿块而死亡。本报告描述了一种罕见的犬甲状腺癌,即甲状腺癌肉瘤,术前表现为脓肿,术后通过组织病理学证实。关键临床信息:尽管在犬中罕见,但甲状腺癌肉瘤也应包括在颈部肿块的鉴别诊断中,特别是在有侵袭性进展的情况下。

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本文引用的文献

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What Is Your Diagnosis?你的诊断是什么?
J Am Vet Med Assoc. 2019 Apr 15;254(8):919-922. doi: 10.2460/javma.254.8.919.
6
Thyroid carcino-sarcoma in a dog.一只狗的甲状腺癌肉瘤
J S Afr Vet Assoc. 2013 Apr 12;84(1):E1-5. doi: 10.4102/jsava.v84i1.120.
7
Caudal mediastinal paraesophageal abscesses in 7 dogs.7只犬的尾侧纵隔食管旁脓肿
Vet Surg. 2012 Feb;41(2):286-91. doi: 10.1111/j.1532-950X.2011.00922.x. Epub 2011 Dec 8.
9
What is your diagnosis? Ventral neck mass in a dog.你的诊断是什么?一只狗颈部腹侧肿物。
Vet Clin Pathol. 2008 Dec;37(4):447-51. doi: 10.1111/j.1939-165X.2008.00066.x.
10
Intracardiac ectopic thyroid carcinosarcoma in a dog.犬心内异位甲状腺癌肉瘤
Vet Pathol. 2008 Jul;45(4):500-4. doi: 10.1354/vp.45-4-500.

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