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小脑的活体结构影像学:超高场的贡献。

In vivo structural imaging of the cerebellum, the contribution of ultra-high fields.

机构信息

Laboratory for Functional and Metabolic Imaging, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

出版信息

Cerebellum. 2012 Jun;11(2):384-91. doi: 10.1007/s12311-010-0189-2.

Abstract

This review covers some of the contributions to date from cerebellar imaging studies performed at ultra-high magnetic fields. A short overview of the general advantages and drawbacks of the use of such high field systems for imaging is given. One of the biggest advantages of imaging at high magnetic fields is the improved spatial resolution, achievable thanks to the increased available signal-to-noise ratio. This high spatial resolution better matches the dimensions of the cerebellar substructures, allowing a better definition of such structures in the images. The implications of the use of high field systems is discussed for several imaging sequences and image contrast mechanisms. This review covers studies which were performed in vivo in both rodents and humans, with a special focus on studies that were directed towards the observation of the different cerebellar layers.

摘要

这篇综述介绍了一些在超高磁场下进行的小脑成像研究的贡献。简要概述了使用此类高场系统进行成像的一般优缺点。在高磁场中成像的最大优势之一是由于信号噪声比的提高而实现的更高的空间分辨率。这种高空间分辨率更好地匹配小脑亚结构的尺寸,从而在图像中更好地定义这些结构。讨论了高场系统的使用对几种成像序列和图像对比机制的影响。本综述涵盖了在啮齿动物和人类体内进行的研究,特别关注了旨在观察不同小脑层的研究。

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