Department of Dermatology, University of Davis, Sacramento, California 95816, USA.
Dermatol Ther. 2010 May-Jun;23(3):230-42. doi: 10.1111/j.1529-8019.2010.01320.x.
Candidiasis, an often encountered oral disease, has been increasing in frequency. Most commonly caused by the overgrowth of Candida albicans, oral candidiasis can be divided into several categories including acute and chronic forms, and angular cheilitis. Risk factors for the development of oral candidiasis include immunosuppression, wearing of dentures, pharmacotherapeutics, smoking, infancy and old age, endocrine dysfunction, and decreased salivation. Oral candidiasis may be asymptomatic. More frequently, however, it is physically uncomfortable, and the patient may complain of burning mouth, dysgeusia, dysphagia, anorexia, and weight loss, leading to nutritional deficiency and impaired quality of life. A plethora of antifungal treatments are available. The overall prognosis of oral candidiasis is good, and rarely is the condition life threatening with invasive or recalcitrant disease.
念珠菌病是一种常见的口腔疾病,其发病率正在不断上升。该病主要由白色念珠菌过度生长引起,可分为急性和慢性两种形式,以及口角炎。口腔念珠菌病的发病危险因素包括免疫抑制、佩戴义齿、药物治疗、吸烟、婴幼儿和老年人、内分泌功能障碍以及唾液分泌减少。口腔念珠菌病可能无症状。然而,更常见的是它会引起身体不适,患者可能会抱怨口腔烧灼感、味觉障碍、吞咽困难、食欲不振和体重减轻,导致营养缺乏和生活质量受损。有许多抗真菌治疗方法。口腔念珠菌病的总体预后良好,很少出现侵袭性或难治性疾病危及生命的情况。