Sherman Robert G, Prusinski Leo, Ravenel Michele Carter, Joralmon Richard A
Oral Medicine Department, Naval Postgraduate Dental School, 8901 Wisconsin Avenue, Bethesda, Maryland 20889, USA.
Quintessence Int. 2002 Jul-Aug;33(7):521-32.
Oral candidosis is the most common opportunistic fungal infection encountered in dentistry. Normally a benign inhabitant of mucous membranes, the fungal organism, Candida albicans, may present serious, even life-threatening infection in specific patient populations. As an opportunistic organism, Candida albicans is extremely responsive to any process resulting in immunosuppression. The clinical manifestations of oral candidosis are variable, occasionally complicating the clinical diagnosis and management. Treatment is often initially rendered based on a provisional clinical diagnosis and supplemented with adjunctive laboratory tests. Specific therapeutic intervention should be tailored to the individual patient, based on the current health status of the patient and the clinical presentation and severity of the infection.
口腔念珠菌病是牙科中最常见的机会性真菌感染。白色念珠菌这种真菌通常是黏膜的良性寄居菌,但在特定患者群体中可能引发严重甚至危及生命的感染。作为一种机会性微生物,白色念珠菌对任何导致免疫抑制的过程都极为敏感。口腔念珠菌病的临床表现多样,有时会使临床诊断和治疗复杂化。治疗通常最初基于临时临床诊断进行,并辅以辅助实验室检查。应根据患者的当前健康状况、感染的临床表现和严重程度,为个体患者量身定制具体的治疗干预措施。