Biondi-Zoccai Giuseppe, Moretti Claudio, Abbate Antonio, Sheiban Imad
Interventional Cardiology, Division of Cardiology, University of Turin, S. Giovanni Battista "Molinette" Hospital, 10126 Turin, Italy.
Cardiovasc Revasc Med. 2010 Jul-Sep;11(3):189-98. doi: 10.1016/j.carrev.2009.04.007.
Symptomatic coronary artery disease may be commonly due to significant atherosclerotic disease involving coronary vessels of relatively small caliber (i.e., with reference vessel diameter <2.75 mm). Whenever medical therapy fails and in other selected cases, revascularization by means of percutaneous coronary intervention (PCI) or bypass surgery is indicated even for small vessel coronary disease. However, despite the numerous developments and improvements in devices and techniques, PCI of small coronary vessels is still fraught with a significant risk of midterm restenosis after both balloon-only PCI and bare-metal stent implantation. Drug-eluting stents, especially those associated with very low angiographic late lumen loss (<0.20 mm), appear to significantly improve angiographic and clinical outcomes after PCI of small coronary vessels. The present article provides a concise and updated review on percutaneous coronary revascularization in patients with symptomatic small vessel coronary artery disease.
有症状的冠状动脉疾病通常可能是由于严重的动脉粥样硬化疾病累及相对小口径的冠状动脉血管（即参考血管直径<2.75毫米）。每当药物治疗失败以及在其他特定情况下，即使对于小血管冠状动脉疾病，经皮冠状动脉介入治疗（PCI）或搭桥手术进行血运重建也是必要的。然而，尽管在器械和技术方面有众多进展和改进，但仅球囊PCI和裸金属支架植入后，小冠状动脉血管的PCI在中期仍有显著的再狭窄风险。药物洗脱支架，尤其是那些与极低的血管造影晚期管腔丢失（<0.20毫米）相关的支架，似乎能显著改善小冠状动脉血管PCI后的血管造影和临床结果。本文对有症状的小血管冠状动脉疾病患者的经皮冠状动脉血运重建进行了简要且最新的综述。
