Arora R, Abou-Bakr A A, Ahmad M S
Department of Pathology, Farwaniya Hospital, Farwaniya, Kuwait.
Gulf J Oncolog. 2010 Jul(8):35-8.
Angiomyofibroblastoma is a rare benign mesenchymal tumor of lower female genital tract. It has characteristic histomorphology and shows myofibroblastic differentiation. Clinically it is imperative to differentiate angiomyofibroblastoma from other mesenchymal tumors of this region especially aggressive angiomyxoma which is locally infiltrative and needs long term followup. We report clinical, histological, and immunohistochemical features of a case of angiomyofibroblastoma and discuss relevant points regarding histogenesis and biological behaviour. We stress the need to recognize this tumor on clinicopathologic basis to avoid any potential therapeutic implications.
血管肌成纤维细胞瘤是女性下生殖道一种罕见的良性间叶性肿瘤。它具有特征性的组织形态学表现，并显示肌成纤维细胞分化。临床上，必须将血管肌成纤维细胞瘤与该区域的其他间叶性肿瘤区分开来，尤其是侵袭性血管黏液瘤，后者具有局部浸润性，需要长期随访。我们报告了1例血管肌成纤维细胞瘤的临床、组织学和免疫组化特征，并讨论了有关组织发生和生物学行为的相关要点。我们强调需要在临床病理基础上认识这种肿瘤，以避免任何潜在的治疗影响。
