Department of Pediatrics, University of Toledo College of Medicine, and Mercy Children's Hospital, Toledo, Ohio 43608, USA.
Curr Opin Pediatr. 2010 Aug;22(4):530-5. doi: 10.1097/MOP.0b013e32833bb81a.
A review of influenza is particularly relevant this year due to the ongoing novel H1N1 influenza pandemic.
Surveillance and clinical data including risk factors for infection and complications due to the current H1N1 pandemic are reviewed. New evidence on the safety of antiviral agents in children and studies on interventions to reduce community transmission of influenza are included. Influenza vaccine efficacy and improving immunization coverage have also been addressed by recent studies.
These studies from the early phase of the pandemic identify the population that are at high risk for complications, and affirm that active surveillance and prevention are important aspects of a public health response. Appropriate use of antiviral agents and improving influenza immunization coverage for all ages continue to be a challenge. Further studies are underway to improve the public health response, and the pandemic H1N1 strain is being incorporated into the 2010 seasonal influenza vaccine.
由于目前正在流行的新型 H1N1 流感，对流感的综述特别有意义。
对当前 H1N1 大流行的监测和临床数据，包括感染和并发症的危险因素进行了综述。新的证据表明，抗病毒药物在儿童中的安全性，以及减少流感在社区传播的干预措施的研究都包含在内。最近的研究还涉及流感疫苗的效果和提高免疫覆盖率。
这些大流行早期的研究确定了易发生并发症的高危人群，并证实积极的监测和预防是公共卫生应对的重要方面。抗病毒药物的合理使用和提高所有年龄段的流感免疫覆盖率仍然是一个挑战。进一步的研究正在进行中，以改善公共卫生应对措施，大流行的 H1N1 株正在被纳入 2010 年季节性流感疫苗。
