Universidade Federal do Maranhão, São Luiz, MA, Brasil.
Arq Bras Cardiol. 2010 Aug;95(2):215-21. doi: 10.1590/s0066-782x2010005000086. Epub 2010 Jul 9.
Detection of hypertensive retinopathy (HR) with direct ophthalmoscopy is part of the assessment of hypertensive patients. Its use has been questioned because of its subjectivity and high interobserver variability.
To determine the prevalence of HR in hypertensive patients under outpatient monitoring, the correlation between diagnosis and ophthalmoscopy and angiography, and to correlate it with other target organ damages.
An observational, analytical and cross-sectional evaluation of 99 patients. Direct ophthalmoscopy and angiography performed by two investigators independently. Classification of RH, as described by Keith, Wagener and Barker.
The prevalence of HR of any grade was higher than 90.0% by both methods. On ophthalmoscopy, we observed grade I abnormalities in 51.0%, grade II in 43.0%, with one patient with grade III HR. On angiography, we observed grade I abnormalities in 42.0% and grade II in 52.0%. We detected three patients with grade III HR, two of which were not detected by ophthalmoscopy. Observers' agreement for the presence and severity of HR was poor with direct ophthalmoscopy and good with angiography. Renal dysfunction, ECG abnormalities (ventricular hypertrophy, pathological Q wave, repolarization abnormalities), and history of stroke were observed in 70.0%, 27.0% and 10.0% of patients, respectively. There was no relationship between the severity of HR and other target organ damages.
We observed a high prevalence of HR using both methods. Observers' agreement for the diagnosis and determination of the severity of HR was better with angiography. In our sample, there was no association of the severity of HR with other target organ damages.
使用直接检眼镜检测高血压性视网膜病变(HR)是评估高血压患者的一部分。由于其主观性和观察者间差异较大,其应用受到质疑。
确定在门诊监测下的高血压患者中 HR 的患病率、诊断与检眼镜和血管造影之间的相关性,并与其他靶器官损伤相关联。
对 99 例患者进行观察性、分析性和横断面评估。由两名研究者独立进行直接检眼镜和血管造影检查。采用 Keith、Wagener 和 Barker 描述的 RH 分类方法。
两种方法的 HR 任何等级的患病率均高于 90.0%。在检眼镜下,我们观察到 51.0%的患者存在 I 级异常,43.0%的患者存在 II 级异常,有 1 例患者存在 III 级 HR。在血管造影下,我们观察到 42.0%的患者存在 I 级异常,52.0%的患者存在 II 级异常。我们发现 3 例患者存在 III 级 HR,其中 2 例未被检眼镜检出。直接检眼镜检查时观察者对 HR 的存在和严重程度的一致性较差,而血管造影检查时一致性较好。肾功能不全、心电图异常(心室肥厚、病理性 Q 波、复极异常)和脑卒中史在 70.0%、27.0%和 10.0%的患者中分别观察到。HR 的严重程度与其他靶器官损伤之间无相关性。
我们使用两种方法均观察到 HR 的高患病率。观察者对 HR 的诊断和严重程度的一致性在血管造影检查时更好。在我们的样本中,HR 的严重程度与其他靶器官损伤之间无关联。