Department of Radiology, The Catholic University of Korea, Daejeon, Korea.
Br J Radiol. 2010 Jul;83(991):e154-7. doi: 10.1259/bjr/19325350.
Ancient schwannomas are rare, encapsulated tumours of long duration and are benign in nature. The tumour is solitary and may grow to a large size before detection of notable degenerative changes. The term "ancient schwannoma" is used to describe a tumour that has undergone such changes, typified by relative loss of Antoni type A tissue, perivascular hyalinisation, calcification, cystic necrosis, haemorrhage and the presence of degenerative nuclei that may be misinterpreted as sarcomatous pleomorphism. We report two cases of ancient schwannoma in the thigh mimicking malignancies. Identifying the fibrous capsule of the mass and a split fat sign using MRI is important for differentiating ancient schwannoma from other malignant tumours.
神经鞘瘤罕见,为长期存在的包膜肿瘤,性质为良性。肿瘤为单发,在出现明显退行性改变之前可能已长至较大。“神经鞘瘤”一词用于描述已发生退行性变的肿瘤,特征为相对缺乏 Antoni A 型组织、血管周围玻璃样变、钙化、囊性坏死、出血和退行性核,这些特征可能被误诊为肉瘤样多形性。我们报告 2 例发生于大腿的酷似恶性肿瘤的神经鞘瘤。MRI 识别肿块的纤维包膜和“分裂脂肪征”对于将神经鞘瘤与其他恶性肿瘤区分开来很重要。