Gill T S, Pande J, Tewari H
Department of Anatomy, Daniel Baugh Institute of Anatomy, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Ecotoxicol Environ Saf. 1991 Feb;21(1):80-91. doi: 10.1016/0147-6513(91)90010-m.
Prolonged exposure (4 weeks) to 6.72 ppb of the organochlorine insecticide endosulfan induced disturbances in the blood and organ chemistry values of a common fish, Barbus conchonius. In blood the total lipids, cholesterol, and proteins were decreased in comparison to unexposed controls, while the free fatty acids (FFA), glucose, total phosphorus, and lactate were increased. Total lipids, FFA, and proteins were augmented in liver; cholesterol, in liver and ovary; and phosphorus and glycogen, in skeletal muscles. Compared to the controls, a decrease was seen in the total lipids (skeletal muscles and ovary), glycogen (liver, brain, and heart), and cholesterol (testes). Hyperlipemia, hyperproteinemia, and hyperlactemia persisted during a recovery period of 1 week in clean water following endosulfan poisoning.
将普通鱼类细纹无须魮暴露于6.72 ppb的有机氯杀虫剂硫丹中4周，会导致其血液和器官化学值出现紊乱。与未暴露的对照组相比，血液中的总脂质、胆固醇和蛋白质含量降低，而游离脂肪酸（FFA）、葡萄糖、总磷和乳酸含量升高。肝脏中的总脂质、FFA和蛋白质增加；肝脏和卵巢中的胆固醇增加；骨骼肌中的磷和糖原增加。与对照组相比，总脂质（骨骼肌和卵巢）、糖原（肝脏、大脑和心脏）和胆固醇（睾丸）含量降低。硫丹中毒后，在清洁水中经过1周的恢复期，高脂血症、高蛋白血症和高乳酸血症仍然存在。
