Sancho Encarna, Andreau Óscar, Villarroel María J, Fernández-Vega Cristina, Tecles Fernando, Martínez-Subiela Silvia, Cerón José J, Ferrando María D
Laboratory of Ecotoxicology, Department of Functional Biology and Physical Anthropology, Faculty of Biological Sciences, University of Valencia, Dr. Moliner 50, 46100-Burjassot (Valencia) Spain.
Department of Animal Medicine and Surgery, Faculty of Veterinary, University of Murcia, 30100 Espinardo (Murcia) Spain.
J Pestic Sci. 2017 Feb 20;42(1):7-15. doi: 10.1584/jpestics.D16-062.
Propanil stress response in the eel () was examined. Eels were exposed to 3.16 mg/L for 72 hr and allowed to recover for 96 hr. Plasma levels of cortisol, lactate dehydrogenase (LDH), alkaline phosphatase (AP), aspartate aminotransferase (AST), cholesterol, triglycerides, glucose, ammonium, lactate, albumin, and total proteins as well as electrolytes (chloride, sodium, potassium, calcium and phosphorus) were determined. As a consequence of exposure, cortisol, AP, AST, and LDH increased. A hyperglycemic condition, together with hyperlactemia, hypoalbuminemia, hypoproteinemia, hypercholesterolemia and hypertriglycemia was registered. Ammonium increased during exposure concomitantly to hyponatremia, hypochloremia, hypocalcemia, hypophosphatemia, and hypokatremia. During recovery, chloride, sodium, potassium, ammonium, albumin and LDH normalized. At the end of the experiment, fish still exhibited hyperglycemia and hyperlactemia. Hypercalcemia was observed. Cholesterol, triglycerides, AP, and AST did not recuperate. These findings are important for assessing potential risks for areas where fish are grown near intensive herbicide use (, paddy fields).
研究了鳗鱼对敌稗的应激反应。将鳗鱼暴露于3.16毫克/升的环境中72小时，然后让其恢复96小时。测定了血浆中皮质醇、乳酸脱氢酶（LDH）、碱性磷酸酶（AP）、天冬氨酸转氨酶（AST）、胆固醇、甘油三酯、葡萄糖、铵、乳酸、白蛋白、总蛋白以及电解质（氯、钠、钾、钙和磷）的水平。暴露的结果是，皮质醇、AP、AST和LDH升高。出现了高血糖症，同时伴有高乳酸血症、低白蛋白血症、低蛋白血症、高胆固醇血症和高甘油三酯血症。暴露期间铵升高，同时伴有低钠血症、低氯血症、低钙血症、低磷血症和低钾血症。恢复期间，氯、钠、钾、铵、白蛋白和LDH恢复正常。在实验结束时，鱼仍表现出高血糖症和高乳酸血症。观察到高钙血症。胆固醇、甘油三酯、AP和AST未恢复。这些发现对于评估在大量使用除草剂（如稻田）附近养殖鱼类地区的潜在风险很重要。
