Ohishi H, Kunisawa S, van der Marel G, van Boom J H, Rich A, Wang A H, Tomita K, Hakoshima T
Osaka University of Pharmaceutical Sciences, Japan.
FEBS Lett. 1991 Jun 24;284(2):238-44. doi: 10.1016/0014-5793(91)80694-x.
The DNA fragment d(CG)3 was co-crystallized with N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized polyamine. The complex crystal contained one polyamine, 3 magnesium cations and one sodium cation per duplex of d(CG)3, and well diffracted the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a left-handed Z-DNA conformation, and the PA(24) molecule electrostatically interacted with the phosphate groups of the d(CG)3 duplex.
DNA片段d(CG)3与N-(2-氨乙基)-1,4-二氨基丁烷（PA(24)，一种化学合成的多胺）共结晶。该复合晶体在d(CG)3的每个双链体中含有一个多胺、3个镁阳离子和一个钠阳离子，并且能很好地衍射高达1.0埃分辨率的X射线强度。d(CG)3呈现左手Z-DNA构象，并且PA(24)分子与d(CG)3双链体的磷酸基团发生静电相互作用。
