钯催化的在氧化条件下通过还原形成π-烯丙基钯中间体的 1,3-二烯与硼酸酯的氢芳基化反应。
Palladium-catalyzed hydroarylation of 1,3-dienes with boronic esters via reductive formation of pi-allyl palladium intermediates under oxidative conditions.
机构信息
Department of Chemistry, University of Utah, 315 South 1400 East, Salt Lake City, Utah 84112-0850, USA.
出版信息
J Am Chem Soc. 2010 Aug 4;132(30):10209-11. doi: 10.1021/ja105010t.
Abstract
A palladium-catalyzed reductive cross-coupling of 1,3-dienes with boronic esters in which a pi-allyl Pd species is generated directly from a 1,3-diene via a Pd-catalyzed aerobic alcohol oxidation is reported. Both the scope of the process and the origin of a highly selective 1,2-addition are discussed.
摘要
报道了钯催化的 1,3-二烯与硼酸酯的还原交叉偶联反应，其中通过钯催化的有氧醇氧化直接从 1,3-二烯生成 π-烯丙基 Pd 物种。讨论了该过程的范围和高选择性 1,2-加成的来源。
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