Washington University, Department of Biomedical Engineering, Optical Imaging Laboratory, St Louis, Missouri 63130-4899, USA.
J Biomed Opt. 2010 May-Jun;15(3):036019. doi: 10.1117/1.3443793.
Photoacoustic tomography (PAT) has been widely used to image optically absorptive objects in both human and animal tissues. For the first time, we present imaging of water with laser-based PAT. We photoacoustically measure the absorption spectra of water-ethanol mixtures at various water concentrations, and then image water-ethanol and pure-water inclusions in gel and a water inclusion in fat tissue. The significant difference in photoacoustic signals between water and fat tissue indicates that the laser-based PAT has the potential to detect water content in tissue.
光声断层扫描(PAT)已被广泛用于对人体和动物组织中的光吸收物体成像。我们首次展示了基于激光的 PAT 对水的成像。我们用光声法测量了不同水浓度下的水-乙醇混合物的吸收光谱,然后对凝胶中的水-乙醇和纯水包合物以及脂肪组织中的纯水包合物进行了成像。水和脂肪组织之间的光声信号的显著差异表明,基于激光的 PAT 有可能检测组织中的含水量。