Pinamonti Maurizio, Vittone Federico, Ghiglione Francesco, Borasi Andrea, Silvestri Stefano, Coverlizza Sergio
Department of Pathology, Humanitas Gradenigo Hospital, Turin, Italy.
Department of Pathology, Civil Hospital of Ivrea, Ivrea, Italy.
Case Rep Surg. 2018 Jun 4;2018:8362012. doi: 10.1155/2018/8362012. eCollection 2018.
Undifferentiated embryonal sarcoma of the liver is a malignancy with poor prognosis observed more frequently in children between 6 and 10 years old and very rarely found in adults. We present a case of embryonal sarcoma of the liver in a 60-year-old woman without significant medical history who presented to our attention with constitutional symptoms. Preoperative assessments did not show alterations in blood chemistry or tumor markers. Imaging studies showed a huge mass lying in the right abdominal quadrants, strictly adherent to the liver. The tumor was partially cystic with a thickened wall, sporadic contrast enhancement, and solid component. The patient underwent excision of the mass with associated liver bisegmentectomy S5-S6. Postoperative course was uneventful. The definitive histological diagnosis revealed the presence of embryonal sarcoma of the liver. We describe the clinical, histopathological, and therapeutic options adopted in the multimodal treatment of this disease.
肝未分化胚胎性肉瘤是一种预后较差的恶性肿瘤，多见于6至10岁儿童，在成人中极为罕见。我们报告一例60岁女性肝胚胎性肉瘤病例，该患者无重大病史，因全身症状前来就诊。术前评估未发现血液生化或肿瘤标志物异常。影像学检查显示右腹象限有一巨大肿块，与肝脏紧密相连。肿瘤部分呈囊性，壁增厚，有散在的对比增强及实性成分。患者接受了肿块切除及相关的肝S5-S6段双叶切除术。术后病程顺利。最终组织学诊断为肝胚胎性肉瘤。我们描述了该疾病多模式治疗中采用的临床、组织病理学及治疗选择。
