LeGrand Susan B, Walsh Declan
Section of Palliative Medicine and Supportive Oncology, The Harry R. Horvitz Center for Palliative Medicine, Cleveland, Ohio, USA.
J Pain Symptom Manage. 2010 Jul;40(1):136-41. doi: 10.1016/j.jpainsymman.2009.12.008.
Nausea and vomiting is a common and troublesome symptom in advanced cancer. There have been different approaches described for the management of nausea and vomiting, specifically empirical and etiological. Scopolamine is listed in textbooks as a useful medication in management of nausea and vomiting in this setting, although there is no published data to support this recommendation. We present three cases that support the use of scopolamine in an etiologically based approach for management of nausea in advanced cancer.
恶心和呕吐是晚期癌症中常见且棘手的症状。针对恶心和呕吐的管理，已有不同的方法被描述，特别是经验性方法和病因性方法。东莨菪碱在教科书中被列为在这种情况下管理恶心和呕吐的一种有用药物，尽管尚无已发表的数据支持这一推荐。我们呈现三例病例，它们支持在基于病因的方法中使用东莨菪碱来管理晚期癌症患者的恶心症状。
