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感染性主动脉人工血管原位新鲜同种异体移植置换术:18个月随访

In situ fresh allograft replacement of an infected aortic prosthetic graft: eighteen months' follow-up.

作者信息

Bahnini A, Ruotolo C, Koskas F, Kieffer E

机构信息

Service de Chirurgie Vasculaire, Groupe Hospitalier Pitié-Salpetrière, Paris, France.

出版信息

J Vasc Surg. 1991 Jul;14(1):98-102.

PMID:2061963
Abstract

We report a case in which an allogenic aortic graft was used to treat the last one of a series of infectious graft complications. The original operation was a Dacron aortobifemoral bypass for aortoiliac occlusive disease in an institution other than ours. The patient was referred for the treatment of the infection of the prosthetic implant. We inserted a prosthetic bypass from the left axillary to the left deep femoral artery, as well as a crossover autogenous saphenous vein graft from the prosthesis to the right deep femoral artery; in the same operation the infected intraabdominal prosthesis was removed with closure of the proximal aortic stump. Subsequent stenosis of the vein graft made it necessary to insert a prosthetic bypass between the descending thoracic aorta and the two deep femoral arteries. Infection of the last named prosthesis made it necessary to remove it and replace it with a tailored allogenic arterial allograft between the infrarenal abdominal aorta and both deep femoral arteries. The patient had an uneventful recovery as the infection was controlled and both lower limbs were salvaged. Eighteen months later the allograft was patent without any signs of degeneration. Further clinical experience under appropriate conditions may prove the use of allografts effective in the treatment of selected cases of aortic prosthetic infection.

摘要

我们报告了一例使用同种异体主动脉移植物治疗一系列感染性移植物并发症中的最后一例的病例。最初的手术是在我们机构以外的一家医院为一名患有主髂动脉闭塞性疾病的患者进行的涤纶主-双股动脉旁路移植术。该患者因人工植入物感染前来就诊。我们从左腋动脉至左股深动脉植入了一段人工血管旁路,同时从人工血管至右股深动脉植入了一段交叉自体大隐静脉移植物;在同一手术中,切除了感染的腹内人工血管并闭合了主动脉近端残端。随后,静脉移植物发生狭窄,因此有必要在胸降主动脉和两条股深动脉之间植入一段人工血管旁路。最后提到的这段人工血管发生感染,因此有必要将其移除,并用一段定制的同种异体动脉移植物替换,该移植物位于肾下腹主动脉和双侧股深动脉之间。由于感染得到控制且双下肢得以挽救,患者恢复顺利。18个月后,同种异体移植物通畅,没有任何退化迹象。在适当条件下的进一步临床经验可能会证明同种异体移植物在治疗某些主动脉人工血管感染病例中是有效的。

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