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产后复吸的预测因素:波兰中部的前瞻性研究。

Predictors of smoking relapse after delivery: prospective study in central Poland.

机构信息

Department of Environmental Epidemiology, Nofer Institute of Occupational Medicine, 8 Teresy Street, Lodz, Poland.

出版信息

Matern Child Health J. 2011 Jul;15(5):579-86. doi: 10.1007/s10995-010-0639-y.

Abstract

The objective of the study was to identify factors which predispose women to smoking relapse postpartum and the factors that prevent the relapse, in order to design effective interventions to reduce the rate of smoking relapse after delivery. A prospective cohort study was conducted in 2004 and 2005 in Lodz, Poland. One hundred thirty-eight women who quit smoking for the pregnancy period were enrolled into the study between 32 and 36 weeks of pregnancy and were followed up at 3 months after delivery. Self-reported non-smoking status at enrollment and postpartum was verified using saliva cotinine level analyzed by liquid chromatography with tandem mass spectrometry (LC-MS/MS). The cut-off point of 10 ng/ml was adopted for the saliva cotinine level. About half of the study population relapsed into smoking within 3 months after delivery. Most (49%) relapses occurred in the first 4 weeks postpartum. Three factors were identified as directly influencing smoking relapse after delivery: need to cope with stressful situations (OR = 4.7; 95% CI 1.7-14.3), type of quitting attempt (OR = 4.0; 95% CI 1.1-16.1), and smoking environment at home (OR = 7.2; 95% CI 2.2-28.3). These three factors accounted for 84.0% (95% CI 52.7-96.1) of relapses. The profile of women who relapse to smoking after delivery can be described as quitting smoking only for pregnancy and postpartum period, resorting to smoking in response to stressful situations, and living with smokers. Those factors should be taken into account while conducting antismoking intervention for pregnant and postpartum women.

摘要

本研究旨在确定导致女性产后吸烟复吸的因素以及预防复吸的因素,以便设计有效的干预措施来降低产后吸烟复吸率。这是一项 2004 年至 2005 年在波兰罗兹进行的前瞻性队列研究。研究纳入了 138 名在妊娠期间戒烟的女性,她们在妊娠 32-36 周时被纳入研究,并在产后 3 个月进行随访。通过液相色谱-串联质谱法(LC-MS/MS)分析唾液可替宁水平,验证入组时和产后的自我报告非吸烟状态。采用 10ng/ml 作为唾液可替宁水平的截断值。研究人群中约有一半在产后 3 个月内复吸。大多数(49%)复吸发生在产后 4 周内。有三个因素被确定为直接影响产后吸烟复吸:需要应对紧张情况(OR=4.7;95%CI 1.7-14.3)、戒烟尝试的类型(OR=4.0;95%CI 1.1-16.1)和家庭吸烟环境(OR=7.2;95%CI 2.2-28.3)。这三个因素占复吸的 84.0%(95%CI 52.7-96.1)。产后复吸的女性特征可以描述为仅为妊娠和产后戒烟、在紧张情况下诉诸吸烟、以及与吸烟者共同生活。在对孕妇和产后妇女进行戒烟干预时,应考虑这些因素。

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