Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
J Intern Med. 2010 Sep;268(3):207-17. doi: 10.1111/j.1365-2796.2010.02253.x. Epub 2010 Jun 8.
Cardiac troponin levels are routinely measured for diagnosing acute myocardial infarction. Cardiac troponin measurements also provide information concerning prognosis and the effect of early intervention in patients with acute coronary syndromes. The recent development of highly sensitive cardiac troponin assays permits detection of very low circulating levels. Use of sensitive troponin assays improves overall diagnostic accuracy in patients with suspected acute coronary syndromes, and these assays provide strong prognostic information in stable coronary artery disease and chronic heart failure. However, increased sensitivity comes with a cost of decreased specificity, and serial testing, as well as clinical context and judgment, is likely to become increasingly important in the interpretation of troponin assay results.
routinely 常规地，定期地； routine 常规的，例行的；measuring 测量；diagnosing 诊断；acute myocardial infarction 急性心肌梗死；troponin 肌钙蛋白；prognosis 预后；effect 影响；intervention 介入治疗；acute coronary syndromes 急性冠脉综合征；highly sensitive 高敏；cardiac troponin assays 心肌钙蛋白检测；detection 检测；low circulating levels 低循环水平；Use 使用；improve 提高；accuracy 准确性；suspected 疑似的；acute coronary syndromes 急性冠脉综合征；stable coronary artery disease 稳定性冠心病；chronic heart failure 慢性心力衰竭；However 然而；increase 增加；sensitivity 敏感性；specificity 特异性；cost 代价；serial testing 连续检测；interpretation 解释；troponin assay results 肌钙蛋白检测结果
