Department of Orthopaedic Surgery U, University of Copenhagen, Rigshospitalet, 2100 København Ø, Denmark.
J Orthop Traumatol. 2010 Sep;11(3):143-8. doi: 10.1007/s10195-010-0098-7. Epub 2010 Jul 15.
The effect of postoperative adaptive bone remodeling following a stemmed femoral implant in revision total knee arthroplasty (rTKA) is unknown. The aim of this study was to evaluate bone mineral density (BMD) changes of the distal femur following cemented rTKA with a 100-mm press-fit stem.
Sixteen consecutive patients were included in the study (age range 40-85 years; mean 63.5 years). NexGen(®) (Zimmer, Warsaw, IN, USA) cemented revision implants were used. All implants had the same press-fit femoral stem length of 100 mm. Clinical examinations with evaluation of the knee function using the Knee Society's Knee Scoring System were used. Measurements of BMD (g/cm(2)) were performed by dual-energy X-ray absorptiometry (DEXA) using a Norland XR-46 (Norland Corp. Fort Atkinson, WI, USA) bone densitometer.
Knee and function scores improved significantly (P = 0.005) from the preoperative values to 1 year of follow-up. In regions of interest (ROI) 1-4, a significant increase in BMD (3.5-6.0%) after 6 months was seen. This increase only remained significant in ROI 4 (4.0%, P = 0.01) at 1 year of follow-up.
The increase in BMD is probably the result of increased mobility and load on the extremity after implantation of a well-functioning rTKA.
在翻修全膝关节置换术(rTKA)中,使用带柄股骨植入物后的术后适应性骨重塑的效果尚不清楚。本研究的目的是评估使用 100-mm 压配合式股骨柄的水泥固定 rTKA 后股骨远端的骨密度(BMD)变化。
本研究纳入了 16 例连续患者(年龄 40-85 岁;平均 63.5 岁)。使用 NexGen(®)(Zimmer,印第安纳州华沙)水泥固定的翻修植入物。所有植入物均具有相同的 100mm 压配合式股骨柄长度。使用膝关节学会膝关节评分系统进行临床检查,评估膝关节功能。使用 Norland XR-46(Norland Corp.,威斯康星州 Fort Atkinson)骨密度仪通过双能 X 射线吸收法(DEXA)测量 BMD(g/cm(2))。
膝关节和功能评分从术前值到 1 年随访时显著提高(P=0.005)。在感兴趣区域(ROI)1-4 中,术后 6 个月 BMD (3.5-6.0%)显著增加。这种增加仅在 1 年随访时在 ROI 4 中仍然显著(4.0%,P=0.01)。
BMD 的增加可能是植入功能良好的 rTKA 后肢体活动度和负荷增加的结果。