Petersen M M, Olsen C, Lauritzen J B, Lund B
Department of Orthopaedic Surgery U, Rigshospitalet, University of Copenhagen, Denmark.
J Arthroplasty. 1995 Feb;10(1):7-11. doi: 10.1016/s0883-5403(05)80094-4.
The aim of the study was to quantitate changes in bone mineral density (BMD) in the distal femur following uncemented porous-coated total knee arthroplasty. Eight patients with total knee arthroplasties (PCA Primary, Howmedica, Rutherford, NJ) (female:male ratio, 6:2; mean age, 70 years; range, 51-77 years) were scanned by dual-photon absorptiometry within 3 months after surgery and at 2 years. An average decrease of 36% (P = .01) was found in BMD behind the anterior flange of the femoral prosthesis. Proximal to the fixation pegs, BMD increased by 22% (P = .12), but behind the posterior flange of the femoral component, BMD remained unchanged (P = .53). Stress shielding anteriorly in the distal femur occurred in all patients examined 2 years after surgery, and the increase in BMD proximal to the fixation pegs was probably a result of increased and altered mechanical loading.
本研究的目的是定量分析非骨水泥型多孔涂层全膝关节置换术后股骨远端骨矿物质密度（BMD）的变化。对8例行全膝关节置换术的患者（PCA原发性，豪美迪克公司，新泽西州卢瑟福）（女性与男性比例为6:2；平均年龄70岁；范围51 - 77岁）在术后3个月内及2年时进行双能X线吸收法扫描。发现股骨假体前凸缘后方的BMD平均下降了36%（P = 0.01）。在固定钉近端，BMD增加了22%（P = 0.12），但在股骨部件后凸缘后方，BMD保持不变（P = 0.53）。术后2年检查的所有患者中均出现股骨远端前方的应力遮挡，固定钉近端BMD的增加可能是机械负荷增加和改变的结果。
