Tadzhiev F S
Ter Arkh. 1991;63(3):68-70.
Experiments on healthy male rats and those with chronic inflammation in the bronchi (CIB) were made to measure the content of testosterone, estradiol, zinc and copper in the blood and in the liquid of bronchoalveolar lavage (LBAL) as well as in the vitally important organs. Attempts were also made to equalize the content of trace elements by means of medicamentous correction in patients suffering from chronic obstructive bronchitis (COB). In CIB, there was a decrease of testosterone concentration in the blood and of zinc concentration in the plasma and formed elements of the blood, lungs, heart, liver, testes and adrenals (p less than 0.05). The zinc level in the LBAL was two times higher, that of copper was three times lower. After zinc sulfate was included into a complex of treatment measures for COB patients, zinc and copper concentrations in the plasma and formed elements of the blood returned to normal in addition to the improvement of the general health status. In the reference group of patients who received conventional symptomatic treatment, the given parameters did not noticeably change.
对健康雄性大鼠以及患有支气管慢性炎症（CIB）的大鼠进行了实验，以测量血液、支气管肺泡灌洗液体（LBAL）以及重要器官中睾酮、雌二醇、锌和铜的含量。还尝试通过药物校正来平衡慢性阻塞性支气管炎（COB）患者体内微量元素的含量。在CIB大鼠中，血液中睾酮浓度以及血浆和血液、肺、心脏、肝脏、睾丸和肾上腺的有形成分中的锌浓度均降低（p<0.05）。LBAL中的锌水平高出两倍，铜水平低三倍。在将硫酸锌纳入COB患者的综合治疗措施后，除了总体健康状况得到改善外，血浆和血液有形成分中的锌和铜浓度恢复正常。在接受传统对症治疗的患者参照组中，上述参数没有明显变化。
