探讨脑刺激实验中背外侧前额叶皮质定位的最佳部位。
Exploring the optimal site for the localization of dorsolateral prefrontal cortex in brain stimulation experiments.
机构信息
Alfred Psychiatry Research Centre, The Alfred and Monash University School of Psychology, Psychiatry and Psychological Medicine, Melbourne, Victoria, Australia.
出版信息
Brain Stimul. 2009 Oct;2(4):234-7. doi: 10.1016/j.brs.2009.03.002. Epub 2009 Apr 3.
BACKGROUND
Dorsolateral prefrontal cortex (DLPFC) is a common target for repetitive transcranial magnetic stimulation (rTMS) experiments and therapeutic protocols.
OBJECTIVE
The aim of this study was to investigate the optimal method for the localization of DLPFC for use in these studies.
METHODS
Twelve healthy subjects underwent a structural magnetic resonance imaging (MRI) scan, a TMS procedure to establish the location of the motor cortex and a neuronavigational procedure to assess the relative position of the DLPFC. Several electroencephalographic (EEG) points and a position 5 cm anterior to motor cortex were established.
RESULTS
The DLPFC site used was identified as being approximately halfway between the EEG points F3 and AF3. This point is considerably more anterior than the point identified by measuring 5 cm anterior to motor cortex.
CONCLUSIONS
EEG points provide a useful way to optimally identify DLPFC.
背景
背外侧前额叶皮质（DLPFC）是重复经颅磁刺激（rTMS）实验和治疗方案的常见靶点。
目的
本研究旨在探讨用于这些研究的 DLPFC 定位的最佳方法。
方法
12 名健康受试者接受了结构磁共振成像（MRI）扫描、TMS 程序以确定运动皮质的位置和神经导航程序以评估 DLPFC 的相对位置。确定了几个脑电图（EEG）点和距运动皮质前 5 厘米的位置。
结果
使用的 DLPFC 部位被确定为大约在 EEG 点 F3 和 AF3 之间的中点。该点比从前运动皮质测量 5 厘米确定的点更靠前。
结论
脑电图点提供了一种优化识别 DLPFC 的有用方法。
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