Trapp Nicholas T, Purgianto Anthony, Taylor Joseph J, Singh Manpreet K, Oberman Lindsay M, Mickey Brian J, Youssef Nagy A, Solzbacher Daniela, Zebley Benjamin, Cabrera Laura Y, Conroy Susan, Cristancho Mario, Richards Jackson R, Flood Michael J, Barbour Tracy, Blumberger Daniel M, Taylor Stephan F, Feifel David, Reti Irving M, McClintock Shawn M, Lisanby Sarah H, Husain Mustafa M
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA, USA.
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Clin Neurophysiol. 2025 Feb;170:206-233. doi: 10.1016/j.clinph.2024.12.015. Epub 2024 Dec 19.
This article updates the prior 2018 consensus statement by the National Network of Depression Centers (NNDC) on the use of transcranial magnetic stimulation (TMS) in the treatment of depression, incorporating recent research and clinical developments. Publications on TMS and depression between September 2016 and April 2024 were identified using methods informed by PRISMA guidelines. The NNDC Neuromodulation Work Group met monthly between October 2022 and April 2024 to define important clinical topics and review pertinent literature. A modified Delphi method was used to achieve consensus. 2,396 abstracts and manuscripts met inclusion criteria for review. The work group generated consensus statements which include an updated narrative review of TMS safety, efficacy, and clinical features of use for depression. Considerations related to training, roles/responsibilities of providers, and documentation are also discussed. TMS continues to demonstrate broad evidence for safety and efficacy in treating depression. Newer forms of TMS are faster and potentially more effective than conventional repetitive TMS. Further exploration of targeting methods, use in special populations, and accelerated protocols is encouraged. This article provides an updated overview of topics relevant to the administration of TMS for depression and summarizes expert, consensus opinion on the practice of TMS in the United States.
本文更新了抑郁中心国家网络（NNDC）2018年关于经颅磁刺激（TMS）治疗抑郁症的共识声明，纳入了近期的研究和临床进展。使用受PRISMA指南启发的方法，确定了2016年9月至2024年4月期间关于TMS和抑郁症的出版物。NNDC神经调节工作组在2022年10月至2024年4月期间每月召开会议，以确定重要的临床主题并审查相关文献。采用改良的德尔菲法达成共识。2396篇摘要和手稿符合纳入审查的标准。工作组生成了共识声明，其中包括对TMS治疗抑郁症的安全性、有效性和临床使用特征的更新叙述性综述。还讨论了与培训、提供者的角色/职责以及记录相关的考虑因素。TMS在治疗抑郁症方面继续展现出广泛的安全性和有效性证据。新型TMS比传统重复TMS更快，可能更有效。鼓励进一步探索靶向方法、在特殊人群中的应用以及加速方案。本文提供了与TMS治疗抑郁症相关主题的最新概述，并总结了美国关于TMS实践的专家共识意见。
