Ogay Vyacheslav, Bae Kyung Hee, Kim Ki Woo, Soh Kwang-Sup
Biomedical Physics Laboratory, Frontier Physics Research Division and Center for Theoretical Physics, Seoul National University, Seoul, Korea.
J Acupunct Meridian Stud. 2009 Jun;2(2):107-17. doi: 10.1016/S2005-2901(09)60042-X.
To show that the characteristic morphological and ultrastructural features of a Bonghan corpuscle and duct presented here are consistent with the description given in the early reports of Bonghan Kim.
We compared the morphological aspects of Bonghan ducts with those of blood and lymphatic capillaries on the ultrastructural level to display the manifestly distinctive nature of the Bonghan system.
The walls of the ductules were observed to be composed of a single layer of endothelial cells with characteristic rod-shaped nuclei and were not surrounded by a basal lamina or by accessory cells, such as pericytes or smooth muscle cells. The abluminal cell membranes of Bonghan ductules were not attached by anchoring filaments to the fibers of extracellular matrices as observed in lymphatic capillaries. The cytoplasmic processes of ductule endothelial cells appear to form overlapping and interdigitated interconnections which completely lack junctional elements. Although the cytoplasm of ductule endothelial cells contained a well-developed rough endoplasmic reticulum and many free ribosomes and polysomes, there was a relatively small number of pinocytotic vesicles and lacks specific organelles, such as Weibel-Palade bodies.
The Bonghan corpuscles are specialized structures consisting of different types of immune cells randomly scattered as single cells in the matrix or clustered in follicle-like formations. Moreover, the Bonghan ductules in the corpuscle contain flowing immune cells and occasionally basophilic bodies.
证明此处呈现的凤汉小体和管道的特征性形态及超微结构特征与凤汉金早期报告中的描述一致。
我们在超微结构水平上比较了凤汉管道与血液和淋巴毛细血管的形态学方面，以展示凤汉系统明显独特的性质。
观察到小管道壁由单层内皮细胞组成，具有特征性的杆状核，且未被基膜或周细胞或平滑肌细胞等辅助细胞包围。凤汉小管道的腔外细胞膜不像在淋巴毛细血管中那样通过锚定丝附着于细胞外基质纤维。小管道内皮细胞的胞质突起似乎形成重叠和相互交错的连接，完全缺乏连接元件。虽然小管道内皮细胞的细胞质含有发育良好的粗面内质网以及许多游离核糖体和多聚核糖体，但吞饮小泡数量相对较少，且缺乏如魏-帕小体等特定细胞器。
凤汉小体是由不同类型免疫细胞组成的特殊结构，这些免疫细胞以单个细胞形式随机散布于基质中或聚集成滤泡样结构。此外，小体中的凤汉小管道含有流动的免疫细胞，偶尔还有嗜碱性小体。
