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EAU 指南:肾细胞癌——2010 年更新版。

EAU guidelines on renal cell carcinoma: the 2010 update.

机构信息

Department of Surgical and Perioperative Sciences, Urology and Andrology, Umeå University, Umeå, Sweden.

出版信息

Eur Urol. 2010 Sep;58(3):398-406. doi: 10.1016/j.eururo.2010.06.032. Epub 2010 Jul 12.

DOI:10.1016/j.eururo.2010.06.032
PMID:20633979
Abstract

CONTEXT AND OBJECTIVES

The European Association of Urology Guideline Group for renal cell carcinoma (RCC) has prepared these guidelines to help clinicians assess the current evidence-based management of RCC and to incorporate the present recommendations into daily clinical practice.

EVIDENCE ACQUISITION

The recommendations provided in the current updated guidelines are based on a thorough review of available RCC guidelines and review articles combined with a systematic literature search using Medline and the Cochrane Central Register of Controlled Trials.

EVIDENCE SYNTHESIS

A number of recent prospective randomised studies concerning RCC are now available with a high level of evidence, whereas earlier publications were based on retrospective analyses, including some larger multicentre validation studies, meta-analyses, and well-designed controlled studies.

CONCLUSIONS

These guidelines contain information for the treatment of an individual patient according to a current standardised general approach. Updated recommendations concerning diagnosis, treatment, and follow-up can improve the clinical handling of patients with RCC.

摘要

背景与目的

欧洲泌尿外科学会肾癌(RCC)指南小组制定了这些指南,以帮助临床医生评估当前基于循证的 RCC 管理,并将目前的建议纳入日常临床实践。

证据获取

当前更新的指南中提供的建议是基于对可用的 RCC 指南和综述文章的全面审查,以及使用 Medline 和 Cochrane 对照试验中心注册库进行的系统文献检索。

证据综合

目前有许多关于 RCC 的高质量证据的前瞻性随机研究,而早期的出版物则基于回顾性分析,包括一些更大的多中心验证研究、荟萃分析和精心设计的对照研究。

结论

这些指南包含了根据当前标准化一般方法治疗个别患者的信息。关于诊断、治疗和随访的更新建议可以改善 RCC 患者的临床处理。

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