Eimoto T, Yanaka M, Kurosawa M, Ikeya F
Cancer. 1978 May;41(5):1929-36. doi: 10.1002/1097-0142(197805)41:5<1929::aid-cncr2820410537>3.0.co;2-s.
A case of plasma cell granuloma (inflammatory pseudotumor) arising in the meninges of cervical spinal cord of a 37-year-old Japanese man is presented. The diagnosis was made by analogy with the similar lesions known in the lung. Its histology was characterized by infiltration of three kinds of cells; histiocytes with slight epithelioid appearance, plasma cells with numerous Russell bodies, and lymphocytes. Electron microscopy of the formalin-fixed tissue was useful for the identification of these cells, particularly of histiocytes. Although extrapulmonary plasma cell granulomas have been reported, this is the first case, to our knowledge, of this type "tumor" in the spinal cord meninges. Differential diagnoses have been briefly discussed.
本文报告了一例发生于一名37岁日本男性颈段脊髓脑膜的浆细胞肉芽肿（炎性假瘤）病例。诊断是通过与肺部已知的类似病变进行类比得出的。其组织学特征为三种细胞浸润：具有轻微上皮样外观的组织细胞、含有大量拉塞尔小体的浆细胞和淋巴细胞。对福尔马林固定组织进行电子显微镜检查有助于识别这些细胞，尤其是组织细胞。虽然肺外浆细胞肉芽肿已有报道，但据我们所知，这是首例发生于脊髓脑膜的此类“肿瘤”。文中还简要讨论了鉴别诊断。
