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淀粉样变性表现为肺梗死:病例报告。

Amyloidosis presenting as pulmonary infarcts: a case report.

机构信息

Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA.

出版信息

J Thorac Imaging. 2010 Nov;25(4):W138-40. doi: 10.1097/RTI.0b013e3181ced01a.

Abstract

Amyloidosis is a multisystem disease characterized by extracellular deposition of complex protein-polysaccharide in a β-pleated configuration. The imaging features in the thorax are well described and are traditionally divided into tracheobronchial, nodular parenchymal, and diffuse alveolar septal subtypes. We describe an unusual case of pulmonary amyloidosis presenting with hemoptysis as a result of pulmonary infarcts related to vascular deposition. With this case, we show that amyloidosis should be considered (along with embolic disease) when vascular insults (infarcts) are seen in multiple vascular territories.

摘要

淀粉样变性是一种多系统疾病,其特征是复杂的蛋白-多糖在β-折叠构象中外分泌沉积。胸部的影像学特征已有详细描述,传统上可分为气管支气管型、结节性实质型和弥漫性肺泡间隔型。我们描述了一例不常见的肺淀粉样变性病例,其表现为咯血,原因是与血管沉积有关的肺梗死。通过这个病例,我们表明当在多个血管区域中看到血管损伤(梗死)时,应考虑淀粉样变性(与栓塞性疾病一起)。

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