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伴有钙化结节和肿块的肺淀粉样变性——六年计算机断层扫描随访：病例报告

Pulmonary amyloidosis with calcified nodules and masses - a six-year computed tomography follow-up: a case report.

作者信息

Vieira Isabela Garcia, Marchiori Edson, Zanetti Gláucia, Cabral Rafael Ferracini, Takayassu Tatiana Chinem, Spilberg Gabriela, Batista Raquel Ribeiro

机构信息

Service of Diagnostic Radiology, Clementino Fraga Filho Universitary Hospital, Rua Prof. Rodolpho Paulo Rocco, 225. CEP 21.941.913. Cidade Universitária. Rio de Janeiro, Brazil.

出版信息

Cases J. 2009 Sep 8;2:6540. doi: 10.4076/1757-1626-2-6540.

DOI:10.4076/1757-1626-2-6540
PMID:19918529
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2769299/
Abstract

INTRODUCTION

Pulmonary amyloidosis is an uncommon disease, characterized by extracellular deposition of fibrillary protein in the lungs. It appears in three forms: tracheobronchial, nodular pulmonary, and alveolar septal. There are few reports of long-term observation of primary pulmonary amyloidosis.

CASE PRESENTATION

We present the case of a 47-year-old man who presented with fever, dyspnea, cough and hemoptysis. Chest radiograph and computed tomography revealed multiple pulmonary nodules and masses. The patient underwent open lung biopsy, which diagnosed pulmonary amyloidosis.

CONCLUSION

Pulmonary nodular amyloidosis should be considered in the differential diagnosis of pulmonary nodules or masses.

摘要

引言

肺淀粉样变性是一种罕见疾病，其特征为肺内纤维状蛋白的细胞外沉积。它以三种形式出现：气管支气管型、结节型肺淀粉样变性和肺泡间隔型。关于原发性肺淀粉样变性的长期观察报告很少。

病例报告

我们报告一例47岁男性患者，其表现为发热、呼吸困难、咳嗽和咯血。胸部X线片和计算机断层扫描显示多个肺结节和肿块。患者接受了开胸肺活检，诊断为肺淀粉样变性。

结论

在肺结节或肿块的鉴别诊断中应考虑肺结节型淀粉样变性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/5d3084e61b0b/1757-1626-0002-0000006540-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/e100e5f4ee32/1757-1626-0002-0000006540-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/03f720f7b537/1757-1626-0002-0000006540-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/6dbd845505c2/1757-1626-0002-0000006540-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/5d3084e61b0b/1757-1626-0002-0000006540-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/e100e5f4ee32/1757-1626-0002-0000006540-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/03f720f7b537/1757-1626-0002-0000006540-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/6dbd845505c2/1757-1626-0002-0000006540-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e0b/2769299/5d3084e61b0b/1757-1626-0002-0000006540-004.jpg

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本文引用的文献

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2
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J Gen Intern Med. 2007 Nov;22(11):1617-20. doi: 10.1007/s11606-007-0324-z. Epub 2007 Sep 12.
3
[Pulmonary nodular amyloidosis].[肺结节性淀粉样变性]
Respirol Case Rep. 2023 May 16;11(6):e01142. doi: 10.1002/rcr2.1142. eCollection 2023 Jun.
4
Post-Mortem Diagnosis of a Rare Case of Massive Nodular Pulmonary Amyloidosis in a Forensic Setting.法医环境下罕见的大量结节性肺淀粉样变性病例的尸检诊断
Acad Forensic Pathol. 2023 Mar;13(1):41-47. doi: 10.1177/19253621231164023. Epub 2023 Apr 18.
5
Uncommon Presentation of Undiagnosed B-Cell Lymphoproliferative Disorder as Nodular Pulmonary Amyloidosis.未诊断的B细胞淋巴增殖性疾病表现为结节性肺淀粉样变性的罕见病例
J Med Cases. 2023 Jan;14(1):36-43. doi: 10.14740/jmc4026. Epub 2023 Jan 18.
6
Lung parenchymal calcifications in a child with cystic fibrosis.一名患有囊性纤维化儿童的肺实质钙化。
Respirol Case Rep. 2022 Mar 31;10(5):e0941. doi: 10.1002/rcr2.941. eCollection 2022 May.
7
Nodular Pulmonary Amyloidosis Mimicking Metastatic Pulmonary Nodules: A case report and review of the literature.酷似转移性肺结节的结节性肺淀粉样变性：一例报告并文献复习
Sultan Qaboos Univ Med J. 2018 Aug;18(3):e393-e396. doi: 10.18295/squmj.2018.18.03.023. Epub 2018 Dec 19.
8
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Intern Emerg Med. 2017 Sep;12(6):899-900. doi: 10.1007/s11739-016-1593-5. Epub 2016 Dec 30.
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10
Respiratory Tract Amyloidosis. State-of-the-Art Review with a Focus on Pulmonary Involvement.呼吸道淀粉样变性。关注肺部受累的最新综述。
Lung. 2015 Dec;193(6):875-83. doi: 10.1007/s00408-015-9791-x. Epub 2015 Aug 27.
Cir Esp. 2007 Jan;81(1):43-5. doi: 10.1016/s0009-739x(07)71256-3.
4
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6
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7
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8
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9
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