Christophe Mérieux Laboratory, IPB, CAMS-Fondation Mérieux and State Key Laboratory for Molecular Virology and Genetic Engineering, Institute of Pathogen Biology, Chinese Academy of Medical Sciences, 9# Dong Dan San Tiao, Dongcheng District, Beijing, PR China.
J Infect. 2010 Oct;61(4):289-98. doi: 10.1016/j.jinf.2010.07.001. Epub 2010 Jul 16.
To evaluate the roles of human rhinoviruses (HRVs) in acute respiratory tract infections (ARTIs) in Chinese adults and determine the association between species of HRV and clinical presentations.
RT-PCR methods were used to detect HRVs in throat and nasal swabs collected from 6104 adult patients with ARTIs from December 2005 to April 2008 in Beijing, China.
HRV strains were detected in 271 ARTIs cases, 65% of which tested positive for HRV-A, 25% for HRV-B, and 10% for HRV-C. Aside from fever, pharyngeal congestion and headache were the most common clinical symptoms observed in the HRVs infected patients. HRV-A infected patients had a higher percentage of upper respiratory symptoms than patients infected by the two other HRV species. Systemic symptoms such as chilliness and myalgia were more frequent in people infected by HRV-B. The three HRV species exhibited unique infection timing when analyzed monthly.
HRV-C can be detected in adult patients with acute upper respiratory tract infections, but is not the predominant species in this population.
评估人类鼻病毒（HRV）在中国成年人急性呼吸道感染（ARTI）中的作用，并确定 HRV 种与临床特征之间的关联。
采用 RT-PCR 方法检测 2005 年 12 月至 2008 年 4 月北京 6104 例成人急性呼吸道感染患者咽拭子和鼻拭子中的 HRV。
在 271 例急性呼吸道感染病例中检测到 HRV 株，其中 65%为 HRV-A，25%为 HRV-B，10%为 HRV-C。除发热外，咽部充血和头痛是 HRV 感染患者最常见的临床症状。与感染其他两种 HRV 株的患者相比，HRV-A 感染患者上呼吸道症状的比例更高。全身性症状如畏寒和肌痛在感染 HRV-B 的患者中更为常见。当按月分析时，三种 HRV 种表现出独特的感染时间。
可在急性上呼吸道感染的成年患者中检测到 HRV-C，但不是该人群中的主要种。
Zotero 插件
