Health Psychology Section, Department of Health Sciences, University Medical Center Groningen, University of Groningen, HPC FA12, POB 196, 9700 AD Groningen, the Netherlands.
Am J Epidemiol. 2010 Aug 15;172(4):386-8. doi: 10.1093/aje/kwq210. Epub 2010 Jul 16.
In this issue of the Journal, Nakaya et al. (Am J Epidemiol. 2010;172(4):377-385) report null findings from a large-scale prospective study of the prognostic value of 2 personality dimensions, neuroticism and extraversion, for cancer risk and mortality. The study stands out because of its exceptionally large sample size and its methodological strengths. The authors discuss the Nakaya et al. study in the context of persistent beliefs about the role of personality in cancer onset and survival despite a pattern of null findings in the literature, as well as the influence of extreme outlier findings from one investigator group that continue to be cited. They question whether it is time for the field to move on from considering a role for personality in cancer to more promising and modifiable factors.
在本期《美国流行病学杂志》（Am J Epidemiol. 2010;172(4):377-385）上，Nakaya 等人报告了一项大规模前瞻性研究的结果，该研究旨在探讨 2 种人格维度（神经质和外向性）对癌症风险和死亡率的预后价值，但未发现显著关联。这项研究之所以引人注目，是因为其样本量非常大，且方法学上具有优势。作者在文中讨论了 Nakaya 等人的研究，内容涉及尽管文献中存在大量阴性结果，但人们对人格在癌症发病和生存中的作用仍存在持续的信念，以及一个研究小组的极端异常值结果的持续影响，这些结果仍被引用。他们质疑，是否是时候让该领域不再考虑人格在癌症中的作用，而转向更有前途和可改变的因素了。
