Department of Orthodontics and Paediatric Dentistry, University of Florence, Florence, Italy.
Int J Paediatr Dent. 2010 Nov;20(6):442-50. doi: 10.1111/j.1365-263X.2010.01063.x.
To evaluate the prevalence of dental abnormalities of the primary and permanent maxillary dentitions in children affected by unilateral (UCLP) and bilateral (BCLP) cleft of the lip and palate.
One hundred and fifty-six Caucasian patients (64 females and 92 males) affected by non-syndromic UCLP or BLCP were selected. A control sample of 1000 subjects (482 males and 518 females) without CLP was selected. All comparisons were carried out by means of z-tests on proportions.
The prevalence rate for missing primary lateral incisors in UCLP subjects was 8.1% and it was 27.9% for the permanent lateral incisors. In BLCP subjects, the prevalence rates were 17% for the primary lateral incisors and 60% for the permanent lateral incisors. The second premolar was absent in 5.4% of UCLP subjects and in 8.8% in the BCLP sample. The statistical analysis revealed significant differences for the prevalence rates of all dental anomalies compared with the control group except for second premolar agenesis.
In both UCLP and BCLP subjects the most prevalent missing teeth were the lateral incisors. The dental anomalies occurred predominantly in the cleft area, thus suggesting that the effect of the cleft disturbance is more local than general on the dentition.
评估单侧唇腭裂（UCLP）和双侧唇腭裂（BCLP）患儿的乳牙和恒牙上颌牙列的牙齿异常的发生率。
选择了 156 名非综合征性 UCLP 或 BCLP 白人患者（64 名女性和 92 名男性）。选择了一个 1000 名无唇腭裂受试者（482 名男性和 518 名女性）的对照组。所有比较均通过比例的 z 检验进行。
UCLP 患者缺失的乳牙侧切牙的患病率为 8.1%，恒牙侧切牙的患病率为 27.9%。在 BCLP 患者中，乳牙侧切牙的患病率为 17%，恒牙侧切牙的患病率为 60%。UCLP 患者的第二前磨牙缺失率为 5.4%，BCLP 样本中为 8.8%。除第二前磨牙缺失外，与对照组相比，所有牙齿异常的患病率均存在统计学差异。
在 UCLP 和 BCLP 患者中，最常见的缺失牙齿是侧切牙。牙齿异常主要发生在裂隙区域，这表明裂隙干扰的影响在牙齿上比在整体上更局部。
