Department of Dental Medicine, Division of Orthodontics and Pediatric Dentistry, Section for Jaw Orthopaedics, Karolinska Institutet, Stockholm, Sweden.
Eur J Orthod. 2012 Oct;34(5):561-70. doi: 10.1093/ejo/cjr074. Epub 2011 Jul 12.
This retrospective study was carried out on consecutively collected dental casts, x-rays, and photos of 129 Swedish children who had been born with non-syndromic unilateral (U) cleft lip (CL), cleft lip and alveolus (CLA), or cleft lip and palate (CLP). The following dental characteristics were investigated in the primary and permanent dentitions: 1. the presence, eruption, position, and shape of the lateral incisor; 2. the prevalence of rotation and enamel hypoplasia of the permanent central incisor; 3. the occurrence of hypodontia outside the cleft region; and 4. the transition from the primary to the succeeding permanent lateral incisor in the cleft region. Patients with clefts involving the palate (UCLP) exhibited a high frequency of hypodontia. In patients with clefts, which did not include the palate, malformed lateral incisors were a common finding. In the primary and permanent dentition, the lateral incisor had erupted distal to the cleft in 31.8 and 24.8 per cent of the UCLA and UCLP patients, respectively. No significant pattern was seen regarding the transition from the primary to the succeeding permanent lateral incisor (P = 0.15). The central incisor was rotated in 55 per cent of the patients and this positional deviation was particularly frequent in cases where the lateral incisor was missing in the premaxilla (P < 0.05). Hypodontia outside the cleft region was recorded in 15.5 per cent of the patients. Patients with UCLP had more often crossbite than patients with a UCL or a UCLA phenotype (P < 0.001).
本回顾性研究对 129 名瑞典单侧非综合征性唇裂(UCL)、唇裂伴牙槽突裂(CLA)或唇裂伴腭裂(CLP)儿童的连续采集的牙列模型、X 光片和照片进行了研究。在恒牙和乳牙中,研究了以下牙齿特征:1. 侧切牙的存在、萌出、位置和形态;2. 恒中切牙旋转和釉质发育不全的发生率;3. 裂隙区以外的缺牙情况;4. 裂隙区的乳侧牙向恒侧牙的过渡。腭裂患者(UCLP)的缺牙发生率较高。在不伴腭裂的患者中,侧切牙畸形较为常见。在恒牙和乳牙中,UCLA 和 UCLP 患者的侧切牙分别有 31.8%和 24.8%萌出在裂隙远中。从乳牙到恒牙侧切牙的过渡没有明显的模式(P=0.15)。55%的患者中恒中切牙发生旋转,在前颌缺失时这种位置偏差尤为常见(P<0.05)。15.5%的患者存在裂隙区以外的缺牙。UCLP 患者的反颌发生率高于 UCL 或 UCLA 表型患者(P<0.001)。